ArticleWorld journal of radiology2026
Predictive value of second-trimester ophthalmic artery Doppler for identifying women at risk for preeclampsia.
Article in World journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPreeclampsia (PE) is a multifactorial hypertensive disorder specific to pregnancy that significantly contributes to maternal and perinatal morbidity and mortality worldwide. According to hospital-based studies, its prevalence in India ranges from 5% to 15%. Despite advances in obstetric care, the early identification of women at risk remains a major clinical challenge. Ophthalmic artery Doppler (OAD), a noninvasive and reproducible imaging technique, provides important information on cerebral autoregulation and maternal vascular resistance with potential exploratory utility in the early detection of PE.
aimTo evaluate the predictive value of maternal OAD indices measured during the second trimester (17-23 weeks of gestation) for the subsequent development of PE in a cohort of initially normotensive pregnant women.
methodsThis prospective observational study, conducted from March 2024 to February 2025, enrolled 90 antenatal women in their second trimester with no prior history of hypertension or renal disease. OAD evaluation was performed using the transorbital approach with the Alpinion E-CUBE 8 ultrasound system, and key Doppler indices were recorded. Participants were subsequently followed through the third trimester to assess the development of PE. Statistical analysis was performed using the independent samples
resultsOut of the 90 participants, 8 (8.89%) developed PE during follow-up. The resistive index (
conclusionMaternal OAD measurements, particularly PR, demonstrated significant associations with the subsequent development of PE in this study cohort. Its noninvasive nature, ease of application, and observed diagnostic performance suggest that it may warrant further evaluation as an adjunctive risk stratification tool in antenatal screening protocols, particularly in resource-limited settings. The early detection and management of high-risk pregnancies could be greatly improved by incorporating OAD into standard obstetric care, potentially improving maternal and perinatal outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.