Evidence map›Paper›PMID 42534128›Full record

ArticleExperimental and therapeutic medicine2026

A prospective study of non-invasive preimplantation genetic testing for Rh status, sex prediction and mtDNA copy number analysis using ddPCR on spent culture media.

Ece Gumusoglu-Acar, Sude Subasi, Merve Cebeci, Zehranur Sisman, Ecenur Karadisogullari, Burcin Karamustafaoglu-Balci, Hale Goksever-Celik, Ercan Bastu, Faruk Buyru, Tuba Gunel

Abstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ece Gumusoglu-AcarDepartment of Molecular Biology and Genetics, Faculty of Science, Istanbul University, Istanbul 34134, Turkey.
Sude SubasiDepartment of Molecular Biotechnology and Genetics, Institute of Science, Istanbul University, Istanbul 34134, Turkey.
Merve CebeciDepartment of Molecular Biology and Genetics, Faculty of Science, Istanbul University, Istanbul 34134, Turkey.
Zehranur SismanDepartment of Molecular Biology and Genetics, Faculty of Science, Istanbul University, Istanbul 34134, Turkey.
Ecenur KaradisogullariDepartment of Molecular Biology and Genetics, Faculty of Science, Istanbul University, Istanbul 34134, Turkey.
Burcin Karamustafaoglu-BalciDepartment of Obstetrics and Gynecology, Istanbul Faculty of Medicine, Istanbul University, Istanbul 34093, Turkey.
Hale Goksever-CelikDepartment of Obstetrics and Gynecology, Acıbadem University, Acıbadem Fulya Hospital, IVF and Endometriosis Center, Istanbul 34394, Turkey.
Ercan BastuDepartment of Obstetrics and Gynecology, Acıbadem University, Acıbadem Fulya Hospital, IVF and Endometriosis Center, Istanbul 34394, Turkey.
Faruk BuyruDepartment of Obstetrics and Gynecology, Acıbadem University, Acıbadem Fulya Hospital, IVF and Endometriosis Center, Istanbul 34394, Turkey.
Tuba GunelDepartment of Molecular Biology and Genetics, Faculty of Science, Istanbul University, Istanbul 34134, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Presence of embryo-derived cell-free DNA (cfDNA) in spent culture medium (SCM) represents a promising non-invasive alternative to the conventional preimplantation genetic testing (PGT). The present study evaluated the feasibility of using cfDNA isolated from SCM to determine Rhesus (Rh) status through Rh blood group D antigen (

Indexed as

in vitro fertilizationmitochondrially encoded cytochrome bnon-invasive preimplantation genetic testingRh blood group D antigensex determining region Yspent culture media

Identifiers

PMID42534128
PMCPMC13419690

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.