Evidence map›Paper›PMID 42533937›Full record

ArticleJournal of military, veteran and family health2023

Reporting of sex and gender in clinical trials of opioids and rehabilitation in military and Veterans with chronic pain.

Goris Nazari, Pavlos Bobos, David M Walton, Jordan Miller, David Pedlar, Joy C MacDermid

Abstract read
In one paragraph

Article in Journal of military, veteran and family health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Goris NazariSchool of Rehabilitation Therapy, Queen's University, Kingston Ontario, Canada.
Pavlos BobosSchool of Physical Therapy, Western University, London, Ontario, Canada.
David M WaltonSchool of Physical Therapy, Western University, London, Ontario, Canada.
Jordan MillerSchool of Rehabilitation Therapy, Queen's University, Kingston Ontario, Canada.
David PedlarCanadian Institute for Military and Veteran Health Research, Queen's University, Kingston, Ontario, Canada.
Joy C MacDermidSchool of Physical Therapy, Western University, London, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study assesses the extent to which published research on pain management in Veterans has considered sex and gender differences in the design and reporting of results. Methods: The study identified randomized clinical trials (RCTs) that included active duty military or Veterans with non-cancer pain who were treated with rehabilitation and/or opioid(s) interventions (vs. any control group) published from January 2000 to February 2021. Authors extracted data on the inclusion of sex/gender in design and reporting using the Sex and Gender Equity in Research guidelines (SAGER) and Sex and Gender Methods Review guidelines to assess sex and gender reporting in the included RCTs. Results: The study included 21 RCTs. Reporting of sex and/or gender according to SAGER guidelines indicated all 21 RCTs did not specify any sex and/or gender information in the title/abstract, introduction, methods, results, or discussion. The reporting of sex and/or gender according to Sex and Gender Methods Review guidelines indicated 21 of 21 RCTs did not analyze to identify sex and/or gender differences in the literature review, research question(s), study design, analysis, or interpretation sections. Discussion: Despite expectations of important sex or gender differences in the effects of opioid or rehabilitation interventions for chronic pain in active duty military personnel or Veterans, no identified RCTs published over a 21-year period adequately reported or analyzed data in accordance with current standards for considering sex and gender. Failure to consider sex and gender in design, analysis, and reporting limits advancement of understanding sex/gender differences in pain management through research.

Indexed as

active dutygendermilitaryopioidspain managementrandomized clinical trialsrehabilitationsexVeterans

Identifiers

PMID42533937
PMCPMC13292971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.