Evidence map›Paper›PMID 42533777›Full record

ArticleInternational journal of urology : official journal of the Japanese Urological Association2026

[

Koji Hatano, Tadashi Watabe, Takero Hirata, Masatoshi Konishi, Tomohiro Kanaki, Masaru Tani, Toshiki Oka, Yu Ishizuya, Takuji Hayashi, Yoshiyuki Yamamoto and 6 more

Abstract read
In one paragraph

Article in International journal of urology : official journal of the Japanese Urological Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Editorial Comment on [International journal of urology : official journal of the Japanese Urological Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Koji HatanoDepartment of Urology, The University of Osaka Graduate School of Medicine, Suita, Japan.ORCID https://orcid.org/0000-0002-8409-5152
Tadashi WatabeDepartment of Radiology, The University of Osaka Graduate School of Medicine, Suita, Japan.ORCID https://orcid.org/0000-0001-8658-2395
Takero HirataDepartment of Radiation Oncology, The University of Osaka Graduate School of Medicine, Suita, Japan.
Masatoshi KonishiDepartment of Urology, The University of Osaka Graduate School of Medicine, Suita, Japan.
Tomohiro KanakiDepartment of Urology, The University of Osaka Graduate School of Medicine, Suita, Japan.
Masaru TaniDepartment of Urology, The University of Osaka Graduate School of Medicine, Suita, Japan.
Toshiki OkaDepartment of Urology, The University of Osaka Graduate School of Medicine, Suita, Japan.
Yu IshizuyaDepartment of Urology, The University of Osaka Graduate School of Medicine, Suita, Japan.
Takuji HayashiDepartment of Urology, The University of Osaka Graduate School of Medicine, Suita, Japan.ORCID https://orcid.org/0000-0003-2030-3087
Yoshiyuki YamamotoDepartment of Urology, The University of Osaka Graduate School of Medicine, Suita, Japan.ORCID https://orcid.org/0000-0002-1271-3521
Taigo KatoDepartment of Urology, The University of Osaka Graduate School of Medicine, Suita, Japan.
Atsunari KawashimaDepartment of Urology, The University of Osaka Graduate School of Medicine, Suita, Japan.ORCID https://orcid.org/0000-0001-9369-4264
Kazutoshi FujitaDepartment of Urology, The University of Osaka Graduate School of Medicine, Suita, Japan.ORCID https://orcid.org/0000-0002-6774-7497
Motohide UemuraDepartment of Urology, The University of Osaka Graduate School of Medicine, Suita, Japan.
Frederik L GieselDepartment of Radiology, The University of Osaka Graduate School of Medicine, Suita, Japan.
Norio NonomuraDepartment of Urology, The University of Osaka Graduate School of Medicine, Suita, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesProstate-specific membrane antigen positron emission tomography (PSMA-PET) is a sensitive imaging modality for detecting recurrent prostate cancer following definitive local therapy. However, evidence on

methodsWe retrospectively analyzed 129 patients with prostate cancer who developed BCR after definitive local therapy and underwent [

resultsPSMA-PET identified recurrent lesions in 83% (n = 107), including local recurrence in 40% (n = 51), lymph node metastasis in 43% (n = 55), and bone metastasis in 26% (n = 33); sites were not mutually exclusive. Metastatic lesions were detectable even at low prostate-specific antigen (PSA) levels (≤ 1.0 ng/mL). In multivariate analysis, Grade Group ≥ 4 was independently associated with metastatic disease (odds ratio [OR], 2.65; 95% confidence interval [CI], 1.06-6.77), whereas a PSA doubling time ≥ 8.7 months was independently associated with a lower likelihood of metastasis (OR, 0.12; 95% CI, 0.05-0.27). Among 55 patients who underwent lesion-directed therapy, PSA declines ≥ 90% were observed in 60% of cases.

conclusionsIn this Japanese cohort with BCR, [

Indexed as

Bone NeoplasmsNeoplasm Recurrence, LocalNiacinamideOligopeptidesPositron-Emission TomographyProstatic NeoplasmsAgedAged, 80 and overFluorine RadioisotopesHumansLymphatic MetastasisMaleMiddle AgedProstateProstate-Specific AntigenRadiopharmaceuticalsFluorine RadioisotopesNiacinamideOligopeptidesProstate-Specific AntigenPSMA-1007Radiopharmaceuticalsmetastasispositron‐emission tomographyprostate cancerprostate‐specific antigenprostate‐specific membrane antigen

Identifiers

PMID42533777
PMCPMC13425049

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.