Evidence map›Paper›PMID 42533508›Full record

ArticleGlobal health, epidemiology and genomics2026

Over Three Decades of Mental Health in Sub-Saharan Africa: An Analysis of GBD Data From 1990 to 2023.

Basile Njei, Yazan A Al-Ajlouni, Samira Y Lemos, Nkengafac Villyen Motaze, Laurent Cleenewerck de Kiev, Luchuo E Bain, Yauba Saidu

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Article in Global health, epidemiology and genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Basile NjeiEngelhardt School of Global Health and Bioethics, Euclid University, Bangui, Central African Republic.ORCID https://orcid.org/0000-0003-0714-4368
Yazan A Al-AjlouniDepartment of Rehabilitation, Montefiore Medical Center, Bronx, New York, USA, montefiore.org.ORCID https://orcid.org/0000-0002-1718-4964
Samira Y LemosDepartment of Diabetes and Endocrinology, Yaoundé General Hospital, Yaoundé, Cameroon.
Nkengafac Villyen MotazeMedicine Usage in South Africa (MUSA), North-West University (NWU), Potchefstroom, South Africa.ORCID https://orcid.org/0000-0003-0227-6425
Laurent Cleenewerck de KievEuler-Franeker Memorial University (EULER), Willemstad, Curaçao, Netherlands.ORCID https://orcid.org/0000-0002-9267-0428
Luchuo E BainAfrican Population and Health Research Center, APHRC, Nairobi, Kenya.ORCID https://orcid.org/0000-0002-6006-2698
Yauba SaiduClinton Health Access Initiative, Yaoundé, Cameroon.ORCID https://orcid.org/0000-0002-0571-0074

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMental disorders are leading causes of disability worldwide but remain underprioritized in many low- and middle-income countries, including sub-Saharan Africa (SSA), where access to care, workforce capacity, and mental health infrastructure remain limited.

objectiveThis study quantified the burden of mental and substance use disorders (SUDs) in SSA from 1990 to 2023 using Global Burden of Disease (GBD) 2023 estimates, with attention to long-term trends, late-period changes, country-level heterogeneity, sex differences, and risk-factor attribution.

methodsWe analyzed GBD 2023 estimates for 46 SSA countries from 1990 to 2023, including prevalence, disability-adjusted life years (DALYs), age-standardized rates, sex-specific estimates, country-level burden, and selected risk factors. Percentage changes were calculated for 1990-2023, with sensitivity analyses for 1990-2019 and 2019-2023 and segmented log-linear trend models using 2019 as the breakpoint.

resultsFrom 1990 to 2023, the age-standardized prevalence rate of mental disorders increased from 11,138.8 to 14,841.0 per 100,000 (+33.24%), while the age-standardized DALY rate increased from 1634.9 to 2218.9 per 100,000 (+35.73%). Anxiety disorders showed the largest relative increases in age-standardized prevalence (+90.99%) and DALY rates (+92.11%). Depressive disorders also increased, while ADHD age-standardized rates remained largely stable. SUDs showed rising absolute burden despite declining age-standardized prevalence and DALY rates. Late-period analyses showed larger increases after 2019, particularly for anxiety disorders. Females had higher age-standardized rates and larger relative increases for anxiety and depressive disorders, whereas males had higher rates of ADHD and SUDs. Among selected risk factors, sexual violence against children had the highest age-standardized attributable DALY rate in 2023, while bullying victimization and intimate partner violence showed the largest relative increases.

conclusionMental and SUDs represent a growing public health challenge in SSA. Strengthening mental health systems, integrating services into primary and general healthcare platforms, expanding SUD prevention and treatment, addressing violence-related risk factors, and reducing stigma are essential to improving mental health outcomes across the region.

Indexed as

Mental DisordersMental HealthSubstance-Related DisordersAdolescentAdultAfrica South of the SaharaDisability-Adjusted Life YearsFemaleGlobal Burden of DiseaseHumansMalePrevalenceRisk Factorsdisability-adjusted life yearsGlobal Burden of Diseasehealth policymental disordersSub-Saharan Africa

Identifiers

PMID42533508
PMCPMC13424614

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.