Evidence map›Paper›PMID 42533317›Full record

ArticleInternational journal of emergency medicine2026

Rapidly progressive Ludwig's angina following self-extraction of a tooth with a nail: a Cannot-Intubate Possible-to-Ventilate scenario managed with LMA bridge to surgical tracheostomy - a case report.

Shallo Alemu Gemeda, Tirsit Endaylalu Worku, Tilaye Tadesse Haile, Getahun Jiru Bedada, Mekonnen Biruk Teklemariam

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Article in International journal of emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Shallo Alemu GemedaDepartment of Emergency and Critical Care Medicine, Salale University Comprehensive Specialized Hospital, Fiche, Ethiopia. shallo_alemu@slu.edu.et.ORCID http://orcid.org/0009-0000-5055-0527
Tirsit Endaylalu WorkuDepartment of Anesthesiology, Critical Care and Pain Medicine, Salale University Comprehensive Specialized Hospital, Fiche, Ethiopia.
Tilaye Tadesse HaileDepartment of Emergency and Critical Care Medicine, Salale University Comprehensive Specialized Hospital, Fiche, Ethiopia.
Getahun Jiru BedadaDepartment of Radiology, Salale University Comprehensive Specialized Hospital, Fiche, Ethiopia.
Mekonnen Biruk TeklemariamDepartment of Emergency and Critical Care Medicine, Salale University Comprehensive Specialized Hospital, Fiche, Ethiopia.ORCID http://orcid.org/0009-0005-9687-2907

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLudwig's angina is a rapidly progressive, potentially fatal polymicrobial cellulitis of the submandibular and sublingual spaces, most commonly of odontogenic origin. Airway compromise may develop within hours, and securing the airway represents the most critical initial intervention. Lemierre's syndrome, septic thrombophlebitis of the internal jugular vein, may complicate deep neck infections and carries significant morbidity. We present a case in which both conditions converged with an extreme difficult airway scenario, managed according to Difficult Airway Society (DAS) guidelines in resource limited setting. CASE PRESENTATION: A 34-year-old previously healthy man presented with a 3-day history of rapidly progressive bilateral neck swelling, high-grade fever, dysphagia, drooling of saliva and respiratory distress after self-extracting a right lower molar tooth with a nail one week prior. On arrival, he had severe trismus, stridor, drooling, tachypnea to 40 breaths per minute and an oxygen saturation of 78% on room air. Direct laryngoscopy failed and video laryngoscopy was not available. A second-generation laryngeal mask airway (LMA) was successfully placed, establishing a Cannot Intubate, Possible to Ventilate (CIPV) scenario. Cricothyroidotomy was attempted but anatomically not feasible due to massive neck swelling. The patient was transferred immediately to the operating room where a surgical tracheostomy was performed while LMA ventilation was maintained. He subsequently developed septic shock, peri-procedural cardiac arrest with initial asystole converting to ventricular tachycardia (VTac) with wide-complex morphology requiring 200 J defibrillation after one CPR cycle and achieving return of spontaneous circulation. Ultrasound and CT of the neck confirmed Lemierre's syndrome with left internal jugular vein thrombosis.

conclusionThis case illustrates the lethal potential of rapidly progressive Ludwig's angina, underscores the importance of early structured airway management following DAS guidelines, and highlights Lemierre's syndrome as a serious complication of deep neck infection. LMA can be a life-saving bridge in the CIPV scenario when front-of-neck access fails.

Indexed as

Cannot intubate possible to ventilateCricothyroidotomyDAS guidelinesDeep neck infectionDifficult airwayLaryngeal mask airwayLemierre’s syndromeLMALudwig’s anginaOdontogenic infectionTracheostomy

Identifiers

PMID42533317
PMCPMC13422294

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.