Evidence map›Paper›PMID 42533262›Full record

ArticleEnvironmental science and pollution research international2026

Bisphenol A disrupts mitochondrial homeostasis and promotes metabolic alterations in cervical cancer cells.

Nadeem Ghani Khan, Divya Adiga, Kannath U Sanjay, Padmalatha Satwadi Rai, Shama Prasada Kabekkodu

Abstract read
In one paragraph

Article in Environmental science and pollution research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nadeem Ghani KhanDepartment of Cell and Molecular Biology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Divya AdigaDepartment of Cell and Molecular Biology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Kannath U SanjayDepartment of Biotechnology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Padmalatha Satwadi RaiDepartment of Biotechnology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Shama Prasada KabekkoduDepartment of Cell and Molecular Biology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India. shama.prasada@manipal.edu.ORCID http://orcid.org/0000-0002-4158-3893

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bisphenol A (BPA), a synthetic endocrine-disrupting chemical, has been implicated in several diseases, including cancer. However, its effects on mitochondrial function in cervical cancer (CC) remain poorly understood. We investigated the effects of BPA on mitochondrial structure and function in SiHa and CaSki CC cell lines. Confocal microscopy revealed that BPA (1 nM-1 µM) disrupted mitochondrial morphology, increased circularity (

Indexed as

Benzhydryl CompoundsMitochondriaPhenolsUterine Cervical NeoplasmsBisphenol A CompoundsCell Line, TumorEndocrine DisruptorsFemaleHomeostasisHumansMembrane Potential, MitochondrialMolecular Docking SimulationOxidative StressReactive Oxygen SpeciesBenzhydryl Compoundsbisphenol ABisphenol A CompoundsEndocrine DisruptorsPhenolsReactive Oxygen SpeciesBisphenol ACervical cancerMetabolic reprogrammingMitochondrial dysfunctionMolecular dockingOxidative stress

Identifiers

PMID42533262
PMCPMC13476184

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.