Articlenpj health systems2026
Estimating the incidence and risk factors of postpartum hemorrhage from the national ENACT network.
Article in npj health systems, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
Aggregated counts from electronic health records (EHRs) provide a rich source of real-world data for investigating critical medical conditions such as postpartum hemorrhage (PPH). We used the Evolve to Next-Gen Accrual to Clinical Trials (ENACT) network, a large, federated network of EHRs, to characterize national trends, risk factors, and comorbidities associated with PPH in a cohort of 705,120 women hospitalized for delivery from 2005 to 2022. During this period, there was a statistically significant increase in the incidence of PPH, consistent with previous studies. Asian women had the highest incidence of PPH (10.33%), followed by Black or African American (8.33%) and American Indian or Alaska Native (8.05%) women. In PPH deliveries, the top-ranked risk factor was severe eclampsia (18.51%), the top-ranked comorbidity was operative vaginal delivery (16.98%), and the commonest cause was uterine atony (83.06%). We demonstrated that a large federated EHR network such as ENACT can be used to generate population-level epidemiological findings, albeit with some limitations.
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