Evidence map›Paper›PMID 42532486›Full record

ArticleContraception2026

Fetal demise duration and bleeding outcomes at the time of dilation and evacuation.

Elisabeth Sulger, Brooke A Levandowski, Emily Fronk, Dana Stuehling, Stacy Sun, Sarah Betstadt

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Article in Contraception, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Elisabeth SulgerDepartment of Obstetrics and Gynecology, University of Rochester Medical Center, 601 Elmwood Ave, Rochester New York 14642, USA. Electronic address: elisabeth.sulger@gmail.com.
Brooke A LevandowskiDepartment of Obstetrics and Gynecology, University of Rochester Medical Center, 601 Elmwood Ave, Rochester New York 14642, USA.
Emily FronkDepartment of Obstetrics and Gynecology, University of Rochester Medical Center, 601 Elmwood Ave, Rochester New York 14642, USA.
Dana StuehlingDepartment of Obstetrics and Gynecology, University of Rochester Medical Center, 601 Elmwood Ave, Rochester New York 14642, USA.
Stacy SunDepartment of Obstetrics and Gynecology, University of Rochester Medical Center, 601 Elmwood Ave, Rochester New York 14642, USA.
Sarah BetstadtDepartment of Obstetrics and Gynecology, University of Rochester Medical Center, 601 Elmwood Ave, Rochester New York 14642, USA.

Funding

The University of Rochester's Clinical and Translational Science InstituteUL1TR002001 · NCATS · UNIVERSITY OF ROCHESTER · PI WILSON, KAREN M., ZAND, MARTIN S · 2016 to 2024
$34.6M
NCATS NIH HHS UL1 TR002001
6 · The paper itself

Abstract

objectivesTo examine associations between time from second trimester intrauterine fetal demise (IUFD) to dilation and evacuation (D&E) and bleeding complications. STUDY

designWe identified 197 patients scheduled for D&E for IUFD at a single academic institution between March 2011 to March 2025. IUFD duration was calculated by subtracting gestational age by fetal biometry from gestational age by obstetric dating, categorized into 0-14 days, 15-28 days, and >28 days. We examined the associations between IUFD duration and bleeding outcomes of disseminated intravascular coagulopathy (DIC) and hemorrhage (EBL >1000mL) using logistic regression.

resultsOf the 189 patients included, durations of fetal demise were 0-14 days (n=61, 32.3%), 15-28 days (n=77, 40.7%), and >28 days (n=51, 27.0%). Bleeding outcomes were 3.2% DIC (n=6) and 2.2% hemorrhage (n=4). Due to low bleeding outcomes, neither were significantly associated with IUFD duration. However, patients >28 days from IUFD had 2.45 higher odds of developing DIC (95% CI 0.2-27.8) and 2.45 higher odds of developing hemorrhage (95% CI 0.2-27.8) compared to patients 0-14 days from IUFD.

conclusionEstimated time from IUFD to D&E is not significantly associated with DIC or hemorrhage. We emphasize the safety of D&E for second trimester IUFDs, especially through the first four weeks of management.

Indexed as

AbortionDilation and evacuationDisseminated intravascular coagulationFetal demisePostoperative hemorrhagePregnancy loss

Identifiers

PMID42532486
PMCPMC13605816

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.