ArticleThe Thoracic and cardiovascular surgeon2026
Applicability of Guideline-Based Aortic Intervention Thresholds in the Indian Population.
Article in The Thoracic and cardiovascular surgeon, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Clinical guidelines for thoracic aortopathy rely on absolute diameter thresholds to guide surveillance and prophylactic intervention. These thresholds, derived largely from Western cohorts, are applied globally, including in populations with smaller baseline vascular dimensions. Methods: We performed a counterfactual, denominator-based analysis comparing the distribution of ascending aortic diameter and its body surface area (BSA)-indexed equivalent in a South Asian general population ( Results: The general population showed a narrow distribution (median 30.2 mm; 95th percentile 37.6 mm; mean indexed diameter 18.5 ± 3.1 mm/m Conclusion: Guideline-based absolute diameter thresholds correspond to an extremely small fraction of this South Asian population, yet dissections remain concentrated in the extreme right tail, a pattern preserved and amplified after BSA indexing. These findings support population-aware interpretation of aortic size thresholds.
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