Evidence map›Paper›PMID 42531997›Full record

ArticleClinical biomechanics (Bristol, Avon)2026

Generalized joint hypermobility and neck pain: Prevalence and functional correlates from a community-based sample.

Rebecca Abbott, Andrew Leroux, Carly Molenaar, Kyle Dalske, Arin Ellingson

Abstract read
In one paragraph

Article in Clinical biomechanics (Bristol, Avon), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rebecca AbbottDivisions of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, MN 55455, USA; Department of Physical Medicine & Rehabilitation, University of Colorado Anschutz, Aurora, CO, USA.
Andrew LerouxDepartment of Biostatistics and Informatics, University of Colorado Anschutz, Aurora, CO, USA.
Carly MolenaarDivisions of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, MN 55455, USA.
Kyle DalskeDivisions of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, MN 55455, USA.
Arin EllingsonDivisions of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address: ellin224@umn.edu.

Funding

NRSA Training CoreTL1TR002493 · NCATS · UNIVERSITY OF MINNESOTA · PI FULKERSON, JAYNE ALLYN · 2018 to 2022
$3.1M
Intersegmental Dynamic Mechanisms of Neck Pain In VivoR03HD097715 · NICHD · UNIVERSITY OF MINNESOTA · PI ELLINGSON, ARIN M · 2019 to 2020
$300k
Generalized joint hypermobility and chronic neck pain: associations with dynamic cervical spine instabilityF32AR082276 · NIAMS · UNIVERSITY OF MINNESOTA · PI ABBOTT, REBECCA · 2023 to 2023
$39k
NCATS NIH HHS TL1 TR002493NIAMS NIH HHS F32 AR082276NICHD NIH HHS R03 HD097715
6 · The paper itself

Abstract

backgroundGeneralized Joint Hypermobility (GJH) is central to hypermobility disorders and common in the general population, yet its role in neck pain and function remains unclear. This study examined relationships among GJH, neck pain burden (pain and disability), and neck function (range of motion [ROM] and strength).

methodsAdults attending a large state fair completed GJH assessments (Beighton Score, Five-Part Questionnaire) and a neck pain survey. A subset also completed neck function testing and the Neck Disability Index. Multivariable regression evaluated associations among GJH, neck pain burden, and neck function, including interaction effects between GJH and neck pain burden.

findings555 participants (336 female/ 219 male) were enrolled. GJH prevalence was higher in females (23.5%) than males (6.8%). Due to small number of males with GJH (n = 15), subgroup and regression analyses were limited to females. Neck pain prevalence was greater in females with GJH than without GJH (24.1% vs 16.0% | n = 366). Among 182 females completing function testing (71 GJH, 111 non-GJH), regression analyses controlling for age, BMI, and neck pain burden showed GJH was associated with greater multi-directional ROM and strength. Significant interactions indicated that associations between disability and function differed according to hypermobility status.

interpretationFemales with GJH had a higher prevalence of neck pain and demonstrated greater ROM and strength than those without GJH. Interactions suggest GJH modifies the relationship between disability and function, supporting the concept that hypermobility may represent a distinct neck pain phenotype. Findings should be interpreted within this relatively healthy community-based cohort.

Indexed as

Joint InstabilityNeck PainAdultFemaleHumansMaleMiddle AgedPrevalenceRange of Motion, Articular

Identifiers

PMID42531997
PMCPMC13520586

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