In one paragraphArticle in American journal of physiology. Heart and circulatory physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
Takuro WashioInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0002-8992-0916 Sarah L HissenInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0003-3181-6961 John D AkinsInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0003-0172-9154 Ryosuke TakedaInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0002-6535-0912 Andrew W D'SouzaInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0001-7024-0446 James P MacNamaraInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0003-2795-6021 Satyam SarmaInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0002-0628-4919 Kevin LutzDepartment of Health Data Science and Biostatistics, O'Donnell School of Public Health, University of Texas Southwestern Medical Center, Dallas, Texas, United States.ORCID 0000-0002-6687-0637 Christopher M HearonInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0002-6561-3532 Tony G BabbInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0002-0515-2164 Benjamin D LevineInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0001-9064-7251 Qi FuInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0002-4218-9126 Funding
Targeting skeletal muscle to improve exercise capacity in heart failure with preserved ejection fraction.P01HL137630 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI BABB, TONY G · 2019 to 2023
$11.4MHypertension and Antihypertensive Therapy in Elderly WomenR01HL091078 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI FU, QI · 2008 to 2011
$1.6MAmerican Heart Association (AHA) 24POST1191431HHS | National Institutes of Health (NIH) P01HL13763HHS | National Institutes of Health (NIH) R01HL091078NHLBI NIH HHS P01 HL137630NHLBI NIH HHS R01 HL091078
6 · The paper itselfAbstract
Heart failure with preserved ejection fraction (HFpEF) is more prevalent in women than in men, and most patients with HFpEF are overweight or obese in the United States. However, whether the impact of obesity on autonomic dysregulation and inflammation differs by sex in HFpEF remains unknown. We investigated sex-specific associations between obesity, inflammation, and muscle sympathetic nerve activity (MSNA) in patients with HFpEF. In 57 HFpEF patients (mean ± SD; 71 ± 7 yr; 37 women, 20 men) and 69 non-HFpEF controls (70 ± 6 yr; 43 women, 26 men), body mass index (BMI), MSNA, and C-reactive protein (CRP) were measured during supine rest. A significant sex-by-BMI interaction was observed for the associations between BMI and MSNA (
Indexed as
Heart FailureMuscle, SkeletalObesityStroke VolumeSympathetic Nervous SystemAgedAged, 80 and overBody Mass IndexCase-Control StudiesC-Reactive ProteinFemaleHumansInflammationMaleMiddle AgedSex FactorsC-Reactive Proteinbody fatC-reactive proteininflammatory markersmuscle sympathetic nerve activitysex differences
Identifiers
PMID42531524
PMCPMC13552271
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