Evidence map›Paper›PMID 42531288›Full record

ArticlePLOS global public health2026

Barriers and facilitators to tele-support psychotherapy versus standard in-person mental health services for youth (15-30 Years) with depression in Kampala District, Uganda.

Jeremiah Mutinye Kwesiga, John Mark Bwanika, Benedict Akimana, Happy Banonya, Brenda Kabakaari, Sowed Mutumba, Sabrina Bakeera Kitaka, Musisi Seggane, Moffat Nyirenda, Etheldreda Nakimuli-Mpungu

Abstract read
In one paragraph

Article in PLOS global public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jeremiah Mutinye KwesigaMedical Research Council, Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine (MRC/UVRI/ LSHTM) Research Unit, Entebbe, Uganda.ORCID https://orcid.org/0000-0001-5507-1664
John Mark BwanikaThe Medical Concierge Group/Rocket Health Africa, Kampala, Uganda.
Benedict AkimanaThe Medical Concierge Group/Rocket Health Africa, Kampala, Uganda.
Happy BanonyaThe Medical Concierge Group/Rocket Health Africa, Kampala, Uganda.
Brenda KabakaariThe Medical Concierge Group/Rocket Health Africa, Kampala, Uganda.
Sowed MutumbaThe Medical Concierge Group/Rocket Health Africa, Kampala, Uganda.
Sabrina Bakeera KitakaDepartment of Pediatrics, College of Health Sciences, Makerere University, Kampala, Uganda.
Musisi SegganeDepartment of Psychiatry, College of Health Sciences, Makerere University, Kampala, Uganda.
Moffat NyirendaMedical Research Council, Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine (MRC/UVRI/ LSHTM) Research Unit, Entebbe, Uganda.
Etheldreda Nakimuli-MpunguMedical Research Council, Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine (MRC/UVRI/ LSHTM) Research Unit, Entebbe, Uganda.ORCID https://orcid.org/0000-0001-6857-8931

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression remains a critical mental health challenge among young people in low-resource settings, where financial, structural, and social barriers frequently limit care access. Digital approaches, including Tele-Support Psychotherapy (TSP), have emerged as promising, scalable alternatives to Standard in-person Mental Health Services (SMHS), yet evidence comparing their implementation remains limited. This study explored facilitators and barriers influencing the feasibility, acceptability and engagement of youths with TSP versus SMHS for depression treatment in Kampala District, Uganda. A qualitative phenomenological study was conducted among youth aged 15-30 years enrolled in a randomized controlled trial evaluating both interventions. Data were collected through semi-structured key informant interviews and focus group discussions with participants and lay counselors and analyzed using deductive thematic analysis guided by the Consolidated Framework for Implementation Research (CFIR). In the parent trial, 95 of 154 participants (61.69%) in the TSP arm and 15 of 146 (10.27%) in the SMHS arm engaged with their assigned intervention; these figures provide contextual background for these qualitative findings. Key facilitators for both interventions included strong social support networks and higher income levels. Technological challenges, such as unreliable mobile phone connectivity, hindered TSP, while high costs and limited awareness were barriers to SMHS. Government policies both supported trust in digital interventions and, in some cases, constrained access while lay-counselor attributes, including on-phone session flexible scheduling and rapport-building skills facilitated TSP. TSP presents a viable alternative to SMHS, particularly for youth facing financial and logistical barriers to accessing facility-based mental health services. However, optimizing its delivery requires addressing technological constraints, ensuring consistent government support, and integrating mental health literacy initiatives. Findings underscore the need for flexible and contextually tailored models that leverage technology and address individual and systemic barriers to enhance mental health service access in resource-constrained settings.

Identifiers

PMID42531288
PMCPMC13422828

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.