Evidence map›Paper›PMID 42531130›Full record

ArticleCell reports2026

Intermembrane coupling between Bcl-xL and the IP

Arijita Ghosh, David Weaver, Chi Li, Gyӧrgy Hajnóczky

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Arijita GhoshMitoCare Center, Department of Pathology and Genomic Medicine, Thomas Jefferson University, Philadelphia, PA 19106, USA.
David WeaverMitoCare Center, Department of Pathology and Genomic Medicine, Thomas Jefferson University, Philadelphia, PA 19106, USA.
Chi LiBrown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY 40292, USA.
Gyӧrgy HajnóczkyMitoCare Center, Department of Pathology and Genomic Medicine, Thomas Jefferson University, Philadelphia, PA 19106, USA. Electronic address: gyorgy.hajnoczky@jefferson.edu.

Funding

ER-mitochondrial communication in calcium signaling, energy metabolism and liver diseaseR01DK125897 · NIDDK · THOMAS JEFFERSON UNIVERSITY · PI CSORDAS, GYORGY, HAJNOCZKY, GYORGY · 2021 to 2025
$2.7M
Developing tools for calcium imaging in ITPR2-linked liver pathogenesisR03TR004644 · NCATS · THOMAS JEFFERSON UNIVERSITY · PI HAJNOCZKY, GYORGY · 2023 to 2023
$156k
NCATS NIH HHS R03 TR004644NIDDK NIH HHS R01 DK125897
6 · The paper itself

Abstract

Bcl-xL, an anti-apoptotic Bcl-2 family protein, engages laterally with Bak/Bax in the outer mitochondrial membrane (OMM) to inhibit apoptosis and interacts with the IP

Indexed as

Bcl-xLcalcium signalingCP: cell biologyCP: metabolismendoplasmic reticulumERMCIP3Rlocal Ca(2+) transfermitochondriaorganellar crosstalk

Identifiers

PMID42531130
PMCPMC13651792

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.