Evidence map›Paper›PMID 42530871›Full record

ArticleBioinformatics (Oxford, England)2026

robustocs: robust optimal contribution selection.

Josh Fogg, Jaime Ortiz-Cuadros, Ivan Pocrnic, J A Julian Hall, Gregor Gorjanc

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Josh FoggThe Maxwell Institute, School of Mathematics, The University of Edinburgh, Edinburgh EH9 3FD, United Kingdom.ORCID 0009-0008-0088-2759
Jaime Ortiz-CuadrosThe Roslin Institute and Royal (Dick) School of Veterinary Science, The University of Edinburgh, Midlothian EH25 9RG, United Kingdom.ORCID 0009-0008-7200-4760
Ivan PocrnicThe Roslin Institute and Royal (Dick) School of Veterinary Science, The University of Edinburgh, Midlothian EH25 9RG, United Kingdom.ORCID 0000-0001-5246-7428
J A Julian HallThe Maxwell Institute, School of Mathematics, The University of Edinburgh, Edinburgh EH9 3FD, United Kingdom.
Gregor GorjancThe Roslin Institute and Royal (Dick) School of Veterinary Science, The University of Edinburgh, Midlothian EH25 9RG, United Kingdom.ORCID 0000-0001-8008-2787

Funding

Harmonized Impact Acceleration Account BBS/E/D/30002275Harmonized Impact Acceleration Account BBS/E/RL/230001AHarmonized Impact Acceleration Account BBS/E/RL/230001C
6 · The paper itself

Abstract

summaryOptimal contribution selection (OCS) is a selective breeding method that manages the conversion of genetic variation into genetic gain to facilitate short-term competitiveness and long-term sustainability of breeding programmes. Traditional approaches to OCS and truncation selection (TS) rely on estimates of breeding values and do not explicitly account for uncertainty in these estimates. Here, we use concepts from robust optimization to formulate a robust optimal contribution selection problem (ROCS) and develop two solutions based on conic optimization and sequential quadratic programming. We implemented these methods in the robustocs Python package, which leverages the Gurobi and HiGHS solvers. Our results show favorable performance when solving the ROCS problem using sequential quadratic programming with the HiGHS solver. We show that classical TS and OCS arise as special cases of the robust selection formulations (RTS and ROCS). We demonstrate the package with a small example, comparing outcomes of TS, RTS, OCS, and ROCS. Compared to TS and OCS, RTS and ROCS find contributions that reduce the uncertainty of genetic gain and group coancestry at the expense of reduced genetic gain. AVAILABILITY AND IMPLEMENTATION: robustocs is implemented in Python and released, with documentation, on GitHub under the MIT license at https://github.com/Foggalong/RobustOCS.

Indexed as

Selection, GeneticSoftwareAlgorithmsGenetic VariationModels, Genetic

Identifiers

PMID42530871
PMCPMC13451081

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.