Evidence map›Paper›PMID 42530339›Full record

ArticlemBio2026

Identification of human transferrin receptor as an entry co-receptor for parvovirus B19 infection of human erythroid progenitor cells.

Shane McFarlin, Kang Ning, Xiujuan Zhang, Cagla Aksu Kuz, Wei Zou, Fang Cheng, Steven Kleiboeker, Mario Mietzsch, Jianming Qiu

Abstract read
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Shane McFarlinDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.ORCID 0009-0002-1817-7915
Kang NingDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Xiujuan ZhangDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Cagla Aksu KuzDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.ORCID 0009-0001-6216-9077
Wei ZouDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Fang ChengDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Steven KleiboekerDepartment of Research and Development, Eurofins Viracor Clinical Diagnostics, Lenexa, Kansas, USA.
Mario MietzschDepartment of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida, USA.ORCID 0000-0001-8957-3363
Jianming QiuDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.ORCID 0000-0001-9850-1695

Funding

Viral and Host Determinants of Parvovirus ReplicationR01AI150877 · NIAID · UNIVERSITY OF KANSAS MEDICAL CENTER · PI QIU, JIANMING · 2020 to 2024
$2.4M
Development of novel approaches for gene editing therapies of cystic fibrosisR01HL174593 · NHLBI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Jianming Qiu, Ziying Yan · 2024 to 2026
$1.9M
Identification of the AAVR-independent AAV entry pathwayR21AI166293 · NIAID · UNIVERSITY OF KANSAS MEDICAL CENTER · PI QIU, JIANMING · 2021 to 2022
$425k
Molecular bases of human parvovirus B19 entryR21AI130613 · NIAID · UNIVERSITY OF KANSAS MEDICAL CENTER · PI QIU, JIANMING · 2018 to 2019
$421k
Studies of the KIAA0319L-mediated productive transduction pathways of rAAV vectorsR21AI180416 · NIAID · UNIVERSITY OF KANSAS MEDICAL CENTER · PI QIU, JIANMING · 2024 to 2025
$419k
NHLBI NIH HHS R01 HL174593NIAID NIH HHS R01 AI150877NIAID NIH HHS R21 AI130613NIAID NIH HHS R21 AI166293NIAID NIH HHS R21 AI180416NIH HHS AI150877NIH HHS AI166293NIH HHS AI180416NIH HHS HL174593
6 · The paper itself

Abstract

Parvovirus B19 (B19V), a member of the genus

Indexed as

Erythroid Precursor CellsParvovirus B19, HumanReceptors, TransferrinReceptors, VirusVirus InternalizationCapsid ProteinsCell LineHumansProtein BindingCapsid Proteinscapsid protein VP1, parvovirus B19Receptors, TransferrinReceptors, Virusco-receptorerythroid progenitor cellsparvovirus B19transferrin receptor

Identifiers

PMID42530339
PMCPMC13556231

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.