Evidence map›Paper›PMID 42530193›Full record

ArticleJACC. Case reports2026

Pseudo-Infarction Reversal in Right Precordial Leads: ECG Evolution in Severe Pulmonary Hypertension.

Lina Wang, Yuxia Cui, Jing Song, Qinghao Zhao, Chongyou Lee, Junxian Song

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lina WangDepartment of Cardiology, Center for Cardiovascular Translational Research, Beijing Key Laboratory of Innovative Drug and Device Translation in Endocrine and Metabolic Diseases, Peking University People's Hospital, Beijing, China.
Yuxia CuiDepartment of Cardiology, Center for Cardiovascular Translational Research, Beijing Key Laboratory of Innovative Drug and Device Translation in Endocrine and Metabolic Diseases, Peking University People's Hospital, Beijing, China.
Jing SongDepartment of Cardiology, Center for Cardiovascular Translational Research, Beijing Key Laboratory of Innovative Drug and Device Translation in Endocrine and Metabolic Diseases, Peking University People's Hospital, Beijing, China.
Qinghao ZhaoDepartment of Cardiology, Center for Cardiovascular Translational Research, Beijing Key Laboratory of Innovative Drug and Device Translation in Endocrine and Metabolic Diseases, Peking University People's Hospital, Beijing, China.
Chongyou LeeDepartment of Cardiology, Center for Cardiovascular Translational Research, Beijing Key Laboratory of Innovative Drug and Device Translation in Endocrine and Metabolic Diseases, Peking University People's Hospital, Beijing, China. Electronic address: ayulee9@126.com.
Junxian SongDepartment of Cardiology, Center for Cardiovascular Translational Research, Beijing Key Laboratory of Innovative Drug and Device Translation in Endocrine and Metabolic Diseases, Peking University People's Hospital, Beijing, China. Electronic address: sjx221@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn acute pulmonary hypertension (PH) crisis causes dynamic electrocardiographic (ECG) changes, but complete post-therapy normalization-especially in post-transplant thrombotic microangiopathy (TMA) patients-is rarely documented. CASE SUMMARY: A 53-year-old man with acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation presented with dyspnea. Right heart catheterization confirmed an acute pulmonary hypertension crisis (mean pulmonary arterial pressure: 52 mm Hg) secondary to thrombotic microangiopathy. Treatment with inhaled nitric oxide and treprostinil led to improvement. Follow-up echocardiography showed normalized pulmonary arterial pressure (35 mm Hg), resolution of ECG abnormalities (including a myocardial infarction pattern in the right precordial leads), and no PH recurrence.

conclusionThis case highlights TMA as a rare cause of reversible, vasoreactive PH after hematopoietic stem cell transplantation and documents the full ECG evolution during PH crisis and recovery. TAKE-HOME MESSAGES: ECG monitoring is essential for diagnosing and tracking acute PH crises in transplant patients. Post-transplant TMA can cause reversible PH, requiring prompt hemodynamic assessment and targeted therapy.

Indexed as

electrocardiogramhematopoietic stem cell transplantationpulmonary hypertensionright heart catheterizationthrombotic microangiopathy

Identifiers

PMID42530193
PMCPMC13420616

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.