Evidence map›Paper›PMID 42529876›Full record

Trial reportPrimary health care research & development2026

Economic evaluation of diverting low-risk patients from the emergency department to adjacent out-of-hours primary care in Belgium.

Jane Phiri, Stefan Morreel, Diana De Graeve, Philippe Beutels, Anthony Pairon, Hilde Philips, Koen Monsieurs, Veronique Verhoeven, Lander Willem

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Primary health care research & development, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jane PhiriDepartment of ELIZA (Primary and Interdisciplinary Care), Universiteit Antwerpen, Antwerp, Belgium.ORCID https://orcid.org/0000-0001-9105-0182
Stefan MorreelDepartment of ELIZA (Primary and Interdisciplinary Care), Universiteit Antwerpen, Antwerp, Belgium.ORCID https://orcid.org/0000-0001-6090-2426
Diana De GraeveDepartment of Economics, Universiteit Antwerpen, Antwerp, Belgium.ORCID https://orcid.org/0000-0002-3098-5352
Philippe BeutelsCentre for Health Economic Research and Modelling Infectious Diseases, Universiteit Antwerpen, Antwerp, Belgium.ORCID https://orcid.org/0000-0001-5034-3595
Anthony PaironDepartment of ELIZA (Primary and Interdisciplinary Care), Universiteit Antwerpen, Antwerp, Belgium.ORCID https://orcid.org/0009-0008-1250-9847
Hilde PhilipsDepartment of ELIZA (Primary and Interdisciplinary Care), Universiteit Antwerpen, Antwerp, Belgium.
Koen MonsieursEmergency Department, Antwerp University Hospital, Universiteit Antwerpen, Antwerp, Belgium.ORCID https://orcid.org/0000-0002-5068-4848
Veronique VerhoevenDepartment of ELIZA (Primary and Interdisciplinary Care), Universiteit Antwerpen, Antwerp, Belgium.ORCID https://orcid.org/0000-0002-3708-6501
Lander WillemDepartment of ELIZA (Primary and Interdisciplinary Care), Universiteit Antwerpen, Antwerp, Belgium.ORCID https://orcid.org/0000-0002-9210-1196

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOut-of-hours primary care (OOH-PC) has been introduced in many health systems to reduce non-urgent emergency department (ED) use. While prior studies suggest potential efficiency gains, economic evaluations rarely stratify outcomes by patient risk, limiting policy relevance. This study assesses the cost-effectiveness of diverting low-risk patients from ED to OOH-PC.

aimCompare direct medical costs, time spent at the facility, and hospitalization probability across risk and care setting subgroups from a societal perspective.

methodsWe analysed data from a cluster-randomized trial conducted in Belgium that examined a nurse-led triage system. Under the study trial's extended Manchester Triage System (eMTS) protocol, patients eligible for primary care were assigned to OOH-PC and are referred to in our study as low-risk, while those assigned to the ED are defined as high-risk. To complement previous work, we stratified costs and effects by risk group. Mixed-effects regression models estimated costs, time at the facility, and hospitalization, with bootstrap confidence intervals. We also calculated the incremental net monetary benefit (INMB).

resultsTreating low-risk patients at the OOH-PC instead of at the ED reduced costs by €24 (€14-€39) per patient, shortened the time spent at the facility by 69 (52-94) minutes. From a societal perspective, the average INMB was €49.5 per low-risk patient. Aggregately, we estimated that the 37 intervention weekends in 2019 led to an average saving of €14,136 in direct medical costs and cumulative time savings of 28 days.

conclusionDiverting low-risk patients from the ED to OOH-PC resulted in cost- and time-savings for low-risk patients at the study site. These findings highlight the potential to improve out-of-hours healthcare delivery to maximize benefits for patients and healthcare systems, although confirmation in other healthcare settings is required before wider implementation.

Indexed as

After-Hours CareCost-Benefit AnalysisEmergency Service, HospitalPrimary Health CareTriageAdultAgedBelgiumCost-Effectiveness AnalysisEmergency Room VisitsFemaleHospitalizationHumansMaleMiddle Agedeconomic evaluationemergency departmenthealthcare savingshospitalizationout-of-hours primary caretime spent at the facilitytriage

Identifiers

PMID42529876
PMCPMC13439030

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.