Evidence map›Paper›PMID 42529779›Full record

ArticleVeterinary medicine international2026

Prevalence of Unregistered, Substandard, and Falsified Veterinary Antimicrobials in Ethiopia: A National Postmarket Quality Surveillance Study.

Belachew Tefera, Belachew Bacha, Nardos Tefera, Gudeta Uma, Tadese Setegn, Bizuayehu Belete, Diriba Daba, Dinsefa Jemal, Yilak Tefera, Hussen Bedu and 10 more

Abstract read
In one paragraph

Article in Veterinary medicine international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Belachew TeferaAnimal Product and Input Quality Testing Center, Ethiopian Agricultural Authority, Akaki Kality District 07 P.O. Box 31303, Addis Ababa, Ethiopia.
Belachew BachaAnimal Product and Input Quality Testing Center, Ethiopian Agricultural Authority, Akaki Kality District 07 P.O. Box 31303, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0002-4162-0471
Nardos TeferaAnimal Product and Input Quality Testing Center, Ethiopian Agricultural Authority, Akaki Kality District 07 P.O. Box 31303, Addis Ababa, Ethiopia.ORCID https://orcid.org/0009-0000-1794-1024
Gudeta UmaAnimal Product and Input Quality Testing Center, Ethiopian Agricultural Authority, Akaki Kality District 07 P.O. Box 31303, Addis Ababa, Ethiopia.
Tadese SetegnAnimal Product and Input Quality Testing Center, Ethiopian Agricultural Authority, Akaki Kality District 07 P.O. Box 31303, Addis Ababa, Ethiopia.
Bizuayehu BeleteAnimal Product and Input Quality Testing Center, Ethiopian Agricultural Authority, Akaki Kality District 07 P.O. Box 31303, Addis Ababa, Ethiopia.
Diriba DabaAnimal Product and Input Quality Testing Center, Ethiopian Agricultural Authority, Akaki Kality District 07 P.O. Box 31303, Addis Ababa, Ethiopia.
Dinsefa JemalAnimal Product and Input Quality Testing Center, Ethiopian Agricultural Authority, Akaki Kality District 07 P.O. Box 31303, Addis Ababa, Ethiopia.
Yilak TeferaAnimal Product and Input Quality Testing Center, Ethiopian Agricultural Authority, Akaki Kality District 07 P.O. Box 31303, Addis Ababa, Ethiopia.
Hussen BeduAnimal Product and Input Quality Testing Center, Ethiopian Agricultural Authority, Akaki Kality District 07 P.O. Box 31303, Addis Ababa, Ethiopia.
Tamiru TilkiAnimal Product and Input Quality Testing Center, Ethiopian Agricultural Authority, Akaki Kality District 07 P.O. Box 31303, Addis Ababa, Ethiopia.
Dagnachew HailemichaelAnimal Product and Input Quality Testing Center, Ethiopian Agricultural Authority, Akaki Kality District 07 P.O. Box 31303, Addis Ababa, Ethiopia.
Solomon KebedeEthiopian Agricultural Authority, Addis Ababa, Ethiopia.
Hamid JemalEthiopian Agricultural Authority, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0003-1641-9888
Tesfa MarewDepartment of Pharmaceutics and Industrial Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, P.O. Box. 1176, Addis Ababa, Ethiopia, aau.edu.et.ORCID https://orcid.org/0000-0002-6734-9982
Dawit TeshomeDepartment of Social and Administrative Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, P.O. Box. 1176, Addis Ababa, Ethiopia, aau.edu.et.ORCID https://orcid.org/0000-0002-0825-9207
Teferi GedifDepartment of Social and Administrative Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, P.O. Box. 1176, Addis Ababa, Ethiopia, aau.edu.et.ORCID https://orcid.org/0000-0001-8500-6708
Esayas GelayeFood and Agricultural Organization of the United Nations, Ethiopia Country Office, P.O. Box: 5536, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0002-7329-8632
Tenaw AndualemFood and Agricultural Organization of the United Nations, Ethiopia Country Office, P.O. Box: 5536, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0002-9411-4097
Ayenew AshenefDepartment of Pharmaceutical Chemistry and Pharmacognosy, School of Pharmacy, College of Health Sciences, Addis Ababa University, P.O. Box. 1176, Addis Ababa, Ethiopia, aau.edu.et.ORCID https://orcid.org/0000-0003-2505-899X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The proliferation of unregistered, substandard, and falsified (SF) veterinary pharmaceuticals represents a critical global threat to animal health, food security, and environmental conservation. In sub-Saharan Africa, these products exacerbate the emergence of antimicrobial resistance (AMR), potentially accelerating the transition toward a "post-antibiotic" era. Despite Ethiopia's relatively developed regulatory framework compared to neighboring states, vulnerabilities such as inadequate diagnostic facilities, porous supply chains, and limited postmarketing surveillance results in enforcement persist. Objective: This descriptive study was conducted to determine the prevalence and quality profile of selected veterinary antimicrobials, including antibacterials, anthelmintics, and antiprotozoals, circulating in the Ethiopian market. Methods: Postmarket quality surveillance (PMS) study was conducted across five administrative regions. A total of 142 samples were collected and evaluated through three distinct regulatory tiers: verification of Ethiopian Agricultural Authority (EAA) registration status, standardized visual/physical screening, and official pharmacopeial (compendial) laboratory testing. Results: The majority of sampled products (95.7%) were imported, predominantly from China (75.7%) and India (15.0%). Primary sampling sites included veterinary retail outlets (50.7%) and clinics (22.9%). Regulatory analysis revealed that 17.9% ( Conclusions: Unregistered and substandard veterinary medicines are circulating in the Ethiopian supply chain, posing severe risks to animal health and contributing to the regional AMR crisis. These findings necessitate urgent, concerted efforts from stakeholders to strengthen the national regulatory system, enhance EAA laboratory capacity, and secure the pharmaceutical supply chain through targeted postmarketing enforcement.

Indexed as

antimicrobial resistanceEthiopiapostmarket quality surveillancesubstandard and falsified (SF) veterinary medicinesveterinary pharmaceutical regulation

Identifiers

PMID42529779
PMCPMC13419081

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.