ReviewChemical & biomedical imaging2026
Advances, Challenges, and Opportunities in Electrochemiluminescence Bioimaging.
Review in Chemical & biomedical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Mechanistic insights into electrochemiluminescence: fueling advances in bioanalysis and imaging.Chemical science · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As an imaging technique triggered by redox reactions at the electrode, electrochemiluminescence (ECL), requiring no external light excitation, is becoming a widely used tool in bioimaging. Taking advantage of its near-zero background and high signal-to-noise ratio (SNR), ECL is increasingly demonstrating its potential as a uniquely quantitative tool for biological analysis. The rapid development of luminophores, electrodes, and optical imaging systems has significantly improved ECL performance, enabling high-spatiotemporal-resolution ECL imaging. Currently, progress in ECL bioimaging has involved in vitro immunoassays, in vivo cell imaging, and heterogeneous tissue imaging. In this review, we highlight the core mechanisms and constructions of ECL bioimaging. Building upon this foundation, its applications in multiscale biology are discussed, from immunoassays to tissue imaging. Despite these advances, ECL bioimaging faces challenges arising from low photon flux and penetration depth. We then highlight the intrinsic challenges and opportunities of ECL bioimaging in terms of spatiotemporal resolution, three-dimensional (3D) excitation, biocompatibility, and multiplex imaging. This review aims to outline a roadmap for the future of ECL bioimaging, which is expected to become a central bioanalytical tool with widespread applications, ranging from basic biological research to clinical diagnostics.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.