Evidence map›Paper›PMID 42529587›Full record

ReviewPrecision chemistry2026

Advances and Challenges in Atomic-Level Growth of Two-Dimensional Single Crystals.

Jinzong Kou, Xuping Shi, Fankai Zeng, Kaihui Liu, Xiaozhi Xu

Abstract readReview
In one paragraph

Review in Precision chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jinzong KouGuangdong Basic Research Center of Excellence for Structure and Fundamental Interactions of Matter, Guangdong Provincial Key Laboratory of Quantum Engineering and Quantum Materials, School of Physics, South China Normal University, Guangzhou 510006, China.
Xuping ShiState Key Laboratory for Mesoscopic Physics, Frontiers Science Center for Nano-optoelectronics, School of Physics, Peking University, Beijing 100871, China.
Fankai ZengGuangdong Basic Research Center of Excellence for Structure and Fundamental Interactions of Matter, Guangdong Provincial Key Laboratory of Quantum Engineering and Quantum Materials, School of Physics, South China Normal University, Guangzhou 510006, China.
Kaihui LiuState Key Laboratory for Mesoscopic Physics, Frontiers Science Center for Nano-optoelectronics, School of Physics, Peking University, Beijing 100871, China.ORCID https://orcid.org/0000-0002-8781-2495
Xiaozhi XuGuangdong Basic Research Center of Excellence for Structure and Fundamental Interactions of Matter, Guangdong Provincial Key Laboratory of Quantum Engineering and Quantum Materials, School of Physics, South China Normal University, Guangzhou 510006, China.ORCID https://orcid.org/0000-0003-1067-9590

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The exceptional electronic, optical, and quantum properties of two-dimensional (2D) single crystals have driven extensive research efforts aimed at developing scalable epitaxial methods for next-generation technologies. Of the various approaches available, atomic-level epitaxial growth has emerged as the most effective technique, enabling the epitaxy of wafer-scale single-crystal films with precise control over crystallographic orientation and thickness. However, it also presents significant challenges related to structural stability, lattice matching, and surface-interfacial engineering. In this review, we aim to summarize the latest representative advancements in the atomic-level epitaxy of large-area 2D single crystals, including conductors (e.g., graphene and borophene), semiconductors (e.g., phosphorene and transition metal dichalcogenides), and insulators (e.g., hexagonal boron nitride and metal oxides) and also discuss techniques for controlling defects and manipulating stacking order, highlighting strategies for achieving single nucleation, aligned multilayer islands, and heterostructure integration. Finally, we outline current challenges, such as thermodynamic instability, defect formation during nucleation, and scalability limitations, as well as offer a forward-looking perspective on how to accelerate the incorporation of 2D single crystals into next-generation electronic, optoelectronic, and quantum devices.

Indexed as

2D single crystalsconductorsepitaxial growthinsulatorssemiconductorstopology

Identifiers

PMID42529587
PMCPMC13417691

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.