Evidence map›Paper›PMID 42529467›Full record

ArticleRSC advances2026

Design, synthesis, molecular docking and molecular dynamics simulations of pyrazolo[3,4-

Sara Y Ewieda, Laila Ziko, Ahmed Elshewy, Mo'men Salem, Mohammed L Ibrahim, Mariam Lotfy Khaled, Mohnad Abdalla, Wafa Ali Eltayb, Mohamed R Elnagar, Mohamed M Tawfik and 2 more

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Optimization of a bis-imine scaffold as a glyoxalase I inhibitor: synthesis, SAR, and docking studies.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sara Y EwiedaPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University Kasr El-Eini Street 11562 Cairo Egypt mohamed.nemr@pharma.cu.edu.eg ahmed.elshewy@pharma.cu.edu.eg.
Laila ZikoDepartment of Biochemistry, School of Life and Medical Sciences, University of Hertfordshire, Hosted by Global Academic Foundation Cairo Egypt.ORCID https://orcid.org/0000-0003-1364-8255
Ahmed ElshewyPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University Kasr El-Eini Street 11562 Cairo Egypt mohamed.nemr@pharma.cu.edu.eg ahmed.elshewy@pharma.cu.edu.eg.ORCID https://orcid.org/0000-0002-4493-3158
Mo'men SalemDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Sinai University - Arish Branch Arish 45511 Egypt.
Mohammed L IbrahimDepartment of Biochemistry, Faculty of Pharmacy, Cairo University Kasr El-Eini Street 11562 Cairo Egypt.ORCID https://orcid.org/0000-0002-1686-0561
Mariam Lotfy KhaledDepartment of Biochemistry, Faculty of Pharmacy, Cairo University Kasr El-Eini Street 11562 Cairo Egypt.ORCID https://orcid.org/0009-0009-2088-3801
Mohnad AbdallaPediatric Research Institute, Children's Hospital Affiliated to Shandong University Jinan Shandong 250022 PR China.ORCID https://orcid.org/0000-0002-1682-5547
Wafa Ali EltaybBiotechnology Department, Faculty of Science and Technology, Shendi University Shendi 11111 Nher Anile Sudan.
Mohamed R ElnagarDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University Cairo 11823 Egypt.ORCID https://orcid.org/0000-0003-0434-2369
Mohamed M TawfikDepartment of Zoology, Faculty of Science, Port Said University Port Said 42526 Egypt.ORCID https://orcid.org/0000-0003-3582-0562
Abdullah Yahya Abdullah AlzahraniDepartment of Chemistry, Faculty of Science, King Khalid University Abha 61413 Saudi Arabia.
Mohamed T M NemrPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University Kasr El-Eini Street 11562 Cairo Egypt mohamed.nemr@pharma.cu.edu.eg ahmed.elshewy@pharma.cu.edu.eg.ORCID https://orcid.org/0000-0002-6650-6587

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new series of pyrazolo[3,4-

Identifiers

PMID42529467
PMCPMC13417795

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.