Evidence map›Paper›PMID 42529454›Full record

ReviewPhysics and imaging in radiation oncology2026

A review on radiological properties of fused deposition modelling material for three-dimensional printing in proton and light ion beam therapy.

Christina Stengl, Christina Mooshammer, Jonas Mahnke, Armin Runz, José Vedelago

Abstract readReview
In one paragraph

Review in Physics and imaging in radiation oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christina StenglDepartment of Radiation Oncology, Heidelberg University Hospital (UKHD), Im Neuenheimer Feld 400, Heidelberg, 69120, Germany.
Christina MooshammerDepartment of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg, 69120, Germany.
Jonas MahnkeDepartment of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg, 69120, Germany.
Armin RunzDepartment of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg, 69120, Germany.
José VedelagoDepartment of Radiation Oncology, Heidelberg University Hospital (UKHD), Im Neuenheimer Feld 400, Heidelberg, 69120, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Purpose: Fused Deposition Modelling (FDM) three-dimensional (3D) printing offers a flexible and economical method for producing radiotherapy phantoms with tailored geometries and material properties. While numerous studies have focused on imaging or photon radiotherapy, research on 3D printing for proton and light ion beam therapy remains limited. Accurate knowledge of the radiological properties of FDM-printed materials is crucial to ensure reliable dose calculation and treatment planning in ion beam therapy. Materials and Methods: A comprehensive literature review was conducted to identify publications reporting relevant radiological parameters, including mass density, computed tomography (CT) number given in Hounsfield units (HU), electron density, and stopping power, for FDM printing filaments. Based on the collected data, an FDM lookup table was generated, summarising the radiological properties of these materials across different printing settings. Results: A total of 17 material classes comprising 70 distinct filaments were analysed and indexed in an open-access lookup table. Polylactic acid (PLA) was the most frequently investigated material, reported in over 34 publications. Among the investigated radiological parameters, the CT number showed the greatest variability for a given material. For samples printed at 100% infill, values ranged from -180 HU to 227 HU for PLA. Recommendations for reducing this variability through standardised reporting are provided. Conclusion: This review provides an overview of FDM 3D printing materials in ion beam therapy. It serves as a practical reference for clinical personnel, medical physicists, and researchers in selecting suitable materials for radiotherapy applications. Moreover, it highlights the need for standardised characterisation methodologies and 3D printing guidelines.

Indexed as

3D printingCT numberElectron densityFused deposition modelling (FDM)Stopping power

Identifiers

PMID42529454
PMCPMC13416827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.