Evidence map›Paper›PMID 42529424›Full record

ArticleFrontiers in microbiology2026

Spatial organization of cutaneous microbiomes reveals putative microbial contributions to host chemical defenses in the American toad.

S Donovan McCammon, Jeremy R Chen See, Justin R Wright, Samantha L C Anderson, Travis J Russell, Regina M Lamendella, Thomas J Firneno

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

S Donovan McCammon *Juniata College, Huntingdon, PA, United States.
Jeremy R Chen See *Juniata College, Huntingdon, PA, United States.
Justin R WrightWright Labs, Huntingdon, PA, United States.
Samantha L C AndersonWright Labs, Huntingdon, PA, United States.
Travis J RussellJuniata College, Huntingdon, PA, United States.
Regina M LamendellaJuniata College, Huntingdon, PA, United States.
Thomas J FirnenoJuniata College, Huntingdon, PA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemical defenses are widely evolved throughout the tree of life. Animals can exploit mutualisms with toxin-producing symbionts as a mechanism of chemical defense. However, this has only begun to be explored in depth, and how these mutualisms may relate to how animals synthesize or acquire their toxins has been even less studied. True toads synthesize their own toxins and offer a novel system to study the interplay between the cutaneous skin microbiome and how it may contribute to toxin synthesis or biotransformation. In this study, we investigated whether the cutaneous microbiome of the American toad (

Indexed as

16S rRNA geneAmerican toad (Anaxyrus americanus)chemical defensesmetagenomicsmicrobiomemutualism

Identifiers

PMID42529424
PMCPMC13416787

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.