ArticleChemical & biomedical imaging2026
Versatile Electrochemiluminescence Imaging Platform for Multiplexed Biosensing and Point-of-Care Application.
Article in Chemical & biomedical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
4 authors.
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Abstract
Electrochemiluminescence (ECL) offers high analytical sensitivity, low optical background, and spatially confined light emission at electrode interfaces, enabling a large global market for bead-based ECL immunoassays. Existing ECL instrumentation remains bulky, costly, and largely confined to centralized laboratories with limited access to true spatially resolved imaging. Here, we present a compact, modular ECL imaging platform that enables low-light, spatially resolved, and temporally synchronized electrochemical-optical measurements. The system integrates a Raspberry Pi 4 controller, a monochrome OV9281 global-shutter camera, and an EmStat4s potentiostat, coordinated through open-source Python software providing sub-100 ms synchronization and full control of camera parameters (resolution, exposure, gain, frame rate, and focus). The complete system, of approximately 21 × 15 × 21 cm, has a component bill of materials of 2337 €, which could be reduced to a few hundred euros by using a custom potentiostat, making it substantially more affordable than commercial ECL instruments. Platform performance was validated using both homogeneous solution-phase and heterogeneous bead-based [Ru-(bpy)
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