Evidence map›Paper›PMID 42529351›Full record

ArticleJACS Au2026

Beyond Histone Demethylation: Mechanisms of

Simahudeen Bathir Jaber Sathik Rifayee, Sudheesh Devadas, Midhun George Thomas, Bhargav Varada, Ethan Sommer, Cassandra Talaba, Christopher Schofield, Christo Z Christov

Abstract read
In one paragraph

Article in JACS Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Simahudeen Bathir Jaber Sathik RifayeeDepartment of Chemistry, Michigan Technological University, Houghton, Michigan 49931, United States.ORCID https://orcid.org/0000-0001-8557-078X
Sudheesh DevadasDepartment of Chemistry, Michigan Technological University, Houghton, Michigan 49931, United States.
Midhun George ThomasDepartment of Chemistry, Michigan Technological University, Houghton, Michigan 49931, United States.ORCID https://orcid.org/0000-0002-6298-7061
Bhargav VaradaDepartment of Chemistry, Michigan Technological University, Houghton, Michigan 49931, United States.
Ethan SommerDepartment of Biomedical Engineering, Michigan Technological University, Houghton, Michigan 49931, United States.
Cassandra TalabaDepartment of Biochemistry and Molecular Biology, Michigan Technological University, Houghton, Michigan 49931, United States.
Christopher SchofieldChemistry Research Laboratory, Department of Chemistry, and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford OX1 3TA, U.K.ORCID https://orcid.org/0000-0002-0290-6565
Christo Z ChristovDepartment of Chemistry, Michigan Technological University, Houghton, Michigan 49931, United States.ORCID https://orcid.org/0000-0002-4481-0246

Funding

Understanding the Ligand Binding by Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Histone DemethylasesR15GM139118 · NIGMS · MICHIGAN TECHNOLOGICAL UNIVERSITY · PI CHRISTOV, CHRISTO ZHIVKOV · 2021 to 2024
$786k
NIGMS NIH HHS R15 GM139118
6 · The paper itself

Abstract

The nonheme Fe-(II)/2-oxoglutarate (2OG)-dependent histone demethylase KDM6B (JMJD3) has demonstrated a capacity for diversity in the oxidative transformations of N

Indexed as

ethylisopropylKDM6BMDmethylQM/MM

Identifiers

PMID42529351
PMCPMC13417232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.