ArticleFrontiers in medicine2026
Two-year outcomes of trabeculo-canalectomy for glaucoma secondary to iridocorneal endothelial syndrome: a retrospective study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The study aimed to evaluate the 2-year outcomes of a new surgical procedure for treating Chinese patients with glaucoma secondary to iridocorneal endothelial syndrome (GS-ICE). Methods: This was a retrospective study involving 26 GS-ICE patients (26 eyes) surgically treated with trabeculo-canalectomy in the First Affiliated Hospital with Nanjing Medical University from January 2015 to June 2024, and postoperatively followed up for 2 years. An intraocular pressure (IOP) of lower than 21 mmHg (1 mmHg = 0.133 kPa) with (conditional success) or without anti-glaucoma medication (complete success) was set as the cut-off value of surgical success. Main outcomes of trabeculo-canalectomy for GS-ICE included IOP, number of medications, surgical success, and complications. Results: A total of 26 GS-ICE patients (26 eyes) with an average age of 48.58 ± 9.61 (27-67) years and a median number of 2 (0-4) anti-glaucoma medication regimens were retrospectively included. Compared to the preoperative value (31.10 ± 11.00 mmHg), the postoperative mean IOP was significantly lower, reaching 13.27 ± 2.68, 15.00 ± 3.77, 15.04 ± 2.81, 16.27 ± 3.03, 16.96 ± 3.12, and 16.89 ± 3.18 mmHg at 1 week, 1 month, 3 months, 6 months, 1 year, and 2 years, respectively ( Conclusion: Trabeculo-canalectomy brings favorable two-year outcomes among GS-ICE patients, including an effective IOP control, a reduction of anti-glaucoma medications, and a low risk of postoperative complications.
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