ReviewFrontiers in neurology
Progress in the diagnosis and treatment of post-traumatic hydrocephalus.
Review in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Post-traumatic hydrocephalus (PTH) is a frequent secondary complication after traumatic brain injury and significantly affects neurological recovery and prognosis. This review summarizes epidemiology, mechanisms, risk factors, diagnostic advances, and treatment strategies to improve clinical recognition and management. Methods: A narrative literature review was conducted using major medical databases to identify clinical, imaging, and experimental studies addressing incidence, pathophysiology, diagnosis, and therapy of PTH. Relevant findings were synthesized qualitatively. Results: PTH occurs across injury severities and is associated with subarachnoid hemorrhage, decompressive craniectomy, infection, and advanced age. Proposed mechanisms include cerebrospinal fluid circulation disturbance, impaired absorption, neuroinflammation, and altered intracranial compliance. Diagnostic accuracy has improved with advanced neuroimaging and dynamic cerebrospinal fluid assessment. Therapeutic approaches have evolved from conventional shunting to individualized strategies incorporating endoscopic techniques and adjustable shunt systems. Discussion: PTH remains underdiagnosed due to heterogeneous presentations. Future efforts should focus on standardized diagnostic criteria and early risk stratification, integration of glymphatic and aquaporin-4 (AQP4) pathways, biomarker- and AI-guided diagnostics, and mechanism-targeted preventive strategies across the acute, subacute, and chronic phases of PTH.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.