Evidence map›Paper›PMID 42529268›Full record

ArticleFrontiers in cell and developmental biology2026

Ric-8A controls Cited2 subcellular localization and transcriptional programs during neural crest development.

Carla Castelli, Andrea Beyer, María José Ruiz, Jossef Guajardo, Lina Mariana Tovar, Juan Ignacio Leal, Ignacio Marín-Videla, Andrés Torres, Jorge Araya, Sergio Bustamante and 4 more

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In one paragraph

Article in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Carla CastelliLaboratory of Signaling and Development (LSD), Department of Biochemistry and Molecular Biology, Group for the Study of Developmental Processes (GDeP), Faculty of Biological Sciences, University of Concepción, Concepción, Chile.
Andrea BeyerDepartamento de Ciencias Biológicas, Facultad de Ciencias de La Vida, Universidad Andres Bello, Talcahuano, Chile.
María José RuizLaboratory of Signaling and Development (LSD), Department of Biochemistry and Molecular Biology, Group for the Study of Developmental Processes (GDeP), Faculty of Biological Sciences, University of Concepción, Concepción, Chile.
Jossef GuajardoLaboratory of Signaling and Development (LSD), Department of Biochemistry and Molecular Biology, Group for the Study of Developmental Processes (GDeP), Faculty of Biological Sciences, University of Concepción, Concepción, Chile.
Lina Mariana TovarLaboratory of Signaling and Development (LSD), Department of Biochemistry and Molecular Biology, Group for the Study of Developmental Processes (GDeP), Faculty of Biological Sciences, University of Concepción, Concepción, Chile.
Juan Ignacio LealLaboratory of Signaling and Development (LSD), Department of Biochemistry and Molecular Biology, Group for the Study of Developmental Processes (GDeP), Faculty of Biological Sciences, University of Concepción, Concepción, Chile.
Ignacio Marín-VidelaLaboratory of Signaling and Development (LSD), Department of Biochemistry and Molecular Biology, Group for the Study of Developmental Processes (GDeP), Faculty of Biological Sciences, University of Concepción, Concepción, Chile.
Andrés TorresLaboratory of Signaling and Development (LSD), Department of Biochemistry and Molecular Biology, Group for the Study of Developmental Processes (GDeP), Faculty of Biological Sciences, University of Concepción, Concepción, Chile.
Jorge ArayaLaboratory of Signaling and Development (LSD), Department of Biochemistry and Molecular Biology, Group for the Study of Developmental Processes (GDeP), Faculty of Biological Sciences, University of Concepción, Concepción, Chile.
Sergio BustamanteLaboratory of Signaling and Development (LSD), Department of Biochemistry and Molecular Biology, Group for the Study of Developmental Processes (GDeP), Faculty of Biological Sciences, University of Concepción, Concepción, Chile.
Alejandro MaureiraLaboratory of Signaling and Development (LSD), Department of Biochemistry and Molecular Biology, Group for the Study of Developmental Processes (GDeP), Faculty of Biological Sciences, University of Concepción, Concepción, Chile.
José L GutiérrezDepartment of Biochemistry and Molecular Biology, Faculty of Biological Sciences, University of Concepción, Concepción, Chile.
Estefanía Tarifeño-SaldiviaGene Expression and Regulation Laboratory (GEaRLab), Department of Biochemistry and Molecular Biology, Faculty of Biological Sciences, University of Concepción, Concepción, Chile.
Marcela TorrejónLaboratory of Signaling and Development (LSD), Department of Biochemistry and Molecular Biology, Group for the Study of Developmental Processes (GDeP), Faculty of Biological Sciences, University of Concepción, Concepción, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neural crest (NC) cells are a highly migratory and multipotent population essential for vertebrate development, whose behavior depends on the integration of signaling pathways, transcriptional programs, and cytoskeletal dynamics. Here, we identify a previously unrecognized functional relationship between the signaling regulator Ric-8A and the transcriptional co-regulator Cited2 during NC development in

Indexed as

Cited2developmentGEFneural crestRic-8Asignalingtranscriptional co-regulator

Identifiers

PMID42529268
PMCPMC13416619

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.