Evidence map›Paper›PMID 42529175›Full record

ArticleFrontiers in medicine2026

Impact of a virtual reality program on the cognitive and psycho-emotional state of seniors with mild cognitive impairment.

Natalia V Sharashkina, Olga N Tkacheva, Elen A Mkhitaryan, Nadezhda G Dudchenko, Nadezhda K Runikhina

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Natalia V SharashkinaPirogov National Research Medical University, Russian Gerontology Research and Clinical Centre, Moscow, Russia.
Olga N TkachevaPirogov National Research Medical University, Russian Gerontology Research and Clinical Centre, Moscow, Russia.
Elen A MkhitaryanPirogov National Research Medical University, Russian Gerontology Research and Clinical Centre, Moscow, Russia.
Nadezhda G DudchenkoPirogov National Research Medical University, Russian Gerontology Research and Clinical Centre, Moscow, Russia.
Nadezhda K RunikhinaPirogov National Research Medical University, Russian Gerontology Research and Clinical Centre, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objectives: Assessment of the efficacy of a virtual reality-based program in improving cognition and affect in patients with mild cognitive impairment during inpatient treatment via randomized controlled trial. Research design and methods: We compared the treatment outcomes between two groups of patients, aged 60 to 89, with mild cognitive impairment and varying comorbid conditions who underwent planned inpatient treatment at the Department of Geriatric Neurology at the Russian Gerontology Clinical Research Center. The experimental group ( Results: Both groups exhibited statistically significant improvements in cognitive function, as measured by the Montreal Cognitive Assessment scale (MoCA), and a reduction in depression symptoms, as indicated by the Geriatric Depression Scale (GDS-15). The main group also showed statistically significant improvement of anxiety and depression subscales of the Hospital Anxiety and Depression Scale (HADS), Discussion and implications: Despite the obvious limitations of the presented study, such as small sample power, lack of blinding and replacement intervention in the control group, results show the promise of further research and application of Virtual reality cognitive training for the stated purposes, demonstrating the probable effectiveness as an additional nonpharmacological treatment for certain cognitive and emotional symptoms in patients with mild cognitive impairment.

Indexed as

cognitive impairmentelderlynonpharmacological interventionspsycho-emotional healthvirtual reality

Identifiers

PMID42529175
PMCPMC13416678

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.