Evidence map›Paper›PMID 42529096›Full record

ReviewFrontiers in psychiatry2026

Beyond Theory of Mind: mentalization as a relational and developmental framework for autism.

Assia Riccioni, Cristina Di Vincenzo, Alessia Sabina De Frenza, Carola Leone, Ilaria Bertoncini, Lucrezia Arturi, Luigi Mazzone, Stefano Vicari, Maria Pontillo

Abstract readReview
In one paragraph

Review in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Assia RiccioniChild Neurology and Psychiatry Unit, Department of Mental and Neurological, Dental and Sensory Organ Health, Policlinico Tor Vergata University Hospital, Rome, Italy.
Cristina Di VincenzoDepartment of Psychology, Università Cattolica del Sacro Cuore, Milan, Italy.
Alessia Sabina De FrenzaChild Neurology and Psychiatry Unit, Department of Mental and Neurological, Dental and Sensory Organ Health, Policlinico Tor Vergata University Hospital, Rome, Italy.
Carola LeoneChild Neurology and Psychiatry Unit, Department of Mental and Neurological, Dental and Sensory Organ Health, Policlinico Tor Vergata University Hospital, Rome, Italy.
Ilaria BertonciniChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Lucrezia ArturiChild Neurology and Psychiatry Unit, Department of Mental and Neurological, Dental and Sensory Organ Health, Policlinico Tor Vergata University Hospital, Rome, Italy.
Luigi MazzoneChild Neurology and Psychiatry Unit, Department of Mental and Neurological, Dental and Sensory Organ Health, Policlinico Tor Vergata University Hospital, Rome, Italy.
Stefano VicariChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Maria PontilloChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autistic individuals and those around them often navigate social and emotional situations in which behaviors, intentions, and affects are difficult to interpret. Supporting mentalizing processes within child-caregiver interactions may help address these challenges; however, a broader conceptual shift is needed, moving beyond a narrow deficit-based perspective toward understanding mentalization as a multidimensional, relational, and developmental process. By shifting the focus from individual deficits to child-caregiver meaning-making processes, this framework may help clarify assessment and intervention targets and inform future research on psychopathological vulnerability in autism. This targeted narrative mini-review therefore aimed to summarize preliminary evidence suggests that other-related mentalizing may show greater difficulties than self-related mentalizing, although this hypothesis requires further replication. Findings also highlight caregiver mentalization, particularly parental reflective functioning, as a key relational process shaping how children's behavior is interpreted, regulated, and responded to over time. In this light, preliminary intervention studies suggest that mentalization-based and mentalization-informed approaches may improve parental reflective functioning, cognitive reappraisal, self-efficacy, and inferential style, with potential indirect benefits for children's emotional outcomes. We therefore propose a relational-developmental framework in which mentalization is conceptualized as a shared and dynamic process of meaning-making under conditions of social and emotional ambiguity. Adopting an individual, relational and developmentally informed perspective may contribute to the development of more precise assessment models, more targeted interventions, and a deeper understanding of mental health vulnerability in autism.

Indexed as

autismco-occurring psychopathologymentalizationmentalization-based treatmentsocial cognitionTheory of Mind

Identifiers

PMID42529096
PMCPMC13415915

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.