ArticleFrontiers in aging neuroscience2026
Fatigue in patients with Parkinson's disease: a cross-sectional study.
Article in Frontiers in aging neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: The purpose of this study is to ascertain the incidence of fatigue and to determine the cross-sectional associate and related variables of fatigue in patients with Parkinson's disease (PD). Methods: A sample of 130 healthy individuals (39.23% male, mean age 64.19 ± 8.70 years) and 130 patients with PD (50.00% males, mean age 65.06 ± 9.04) were enrolled in the study. All participants were evaluated using the Fatigue Severity Scale (FSS), Mini-Mental State Examination (MMSE), Hamilton anxiety scale (HAMA), and Hamilton depression scale (HAMD). Patients with PD were assessed with the Unified Parkinson's Disease Rating Scale (UPDRS), Hoehn & Yahr staging, the MMSE, HAMA, HAMD, the Parkinson's Disease Sleep scale-2 (PDSS-2), and Parkinson's Disease Questionnaire-39 (PDQ-39). Results: The PD group exhibited significantly higher scores in the FSS ( Conclusion: Patients with Parkinson's disease experience a higher incidence of distressing fatigue compared to healthy individuals. The significant prevalence of fatigue among these patients is linked to various motor and non-motor symptoms.
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