ArticleFrontiers in endocrinology2026
Admission hyperglycemia, in-hospital glycemic management, and discharge outcomes in acute ischemic stroke: a UAE comprehensive stroke center cohort.
Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Hyperglycemia at presentation is common after acute ischemic stroke and is associated with worse functional outcomes. We examined whether admission hyperglycemia independently predicted unfavorable discharge outcomes, quantified adherence to the SHINE trial-aligned management standards, and tested the stress hyperglycemia ratio (SHR) as an alternative exposure variable. Methods: This single-center retrospective cohort study included 218 consecutive adults with acute ischemic stroke admitted to the Tawam Stroke Center, Al Ain, United Arab Emirates, between July 1 and December 31, 2023. The primary exposure was an admission capillary glucose level >7.8 mmol/L. Two co-primary outcomes were defined Results: Admission hyperglycemia (51.7%) was associated with unfavorable mRS (adjusted OR 3.43, 95% CI 1.33-8.87, Conclusions: Admission hyperglycemia tripled the adjusted odds of unfavorable discharge outcome and identified patients receiving non-adherent management. Structured admission orders, q6h monitoring and routine HbA1c testing are immediate, low-cost quality improvement targets for Gulf stroke services.
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