Evidence map›Paper›PMID 42528643›Full record

ArticleFrontiers in physiology2026

DCR-like restrictive resuscitation is associated with enhanced oxygen metabolism, coagulation recovery, and reduced inflammation in severe chest trauma and shock.

Zhi Hu, Tingzhong Wang, Yuejiao Wei, Xiaolin Hou, Qiang Song

Abstract read
In one paragraph

Article in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhi HuDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Tingzhong WangDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yuejiao WeiDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Xiaolin HouDepartment of Cardiovascular Medicine, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital (Affiliated Hospital of University of Electronic Science and Technology of China), Sichuan, Chengdu, China.
Qiang SongDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The optimal fluid resuscitation strategy for severe chest trauma with hemorrhagic shock remains debated, with limited evidence incorporating comprehensive physiological endpoints. This study compared a restrictive (damage-control resuscitation-like) strategy versus conventional crystalloid-predominant resuscitation in this high-risk population. Methods: This single-center retrospective cohort study used propensity score matching (1:1) to balance age, sex, Injury Severity Score, and shock severity, yielding 200 matched patients (100 per group). Outcomes included 28-day survival, major complications (ARDS, DIC, MODS), ventilator- and ICU-free days, and serial (0-72 h) assessments of oxygen metabolism (SvO Results: The restrictive group received significantly less total fluid (1985 ± 325 vs. 2846 ± 492 mL, Conclusion: In this observational, single-center study, a DCR-like restrictive strategy was associated with superior physiological trajectories and improved short-term clinical outcomes compared with conventional resuscitation. These hypothesis-generating findings do not establish causality and underscore the need for prospective randomized controlled trials before any practice change.

Indexed as

chest traumacoagulationfluid resuscitationhemorrhagic shockinflammationoxygen metabolismpropensity score matchingrestrictive strategy

Identifiers

PMID42528643
PMCPMC13414272

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.