ArticleFrontiers in oncology2026
Giant solid pseudopapillary neoplasm of the pancreas in an adolescent girl: a case report with narrative review.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Solid pseudopapillary neoplasm is a rare epithelial tumor of the pancreas with low malignant potential and a marked predilection for adolescent girls and young women. Although the overall prognosis is favorable after complete resection, preoperative characterization and surgical planning become more challenging in giant tumors with intratumoral degeneration, hemorrhage, and adjacent vascular compression. We report a 15-year-old girl who presented with acute abdominal pain persisting for 24 hours after strenuous physical activity. Imaging revealed a giant mixed solid-cystic mass in the pancreatic body and tail, and computed tomography angiography and venography demonstrated narrowing of the splenic vein with collateral venous circulation. After multidisciplinary assessment of oncologic safety and perioperative bleeding risk, the patient underwent laparoscopic distal pancreatectomy with splenectomy. Histopathology confirmed solid pseudopapillary neoplasm with negative margins and no nodal metastasis; ectopic splenic tissue was identified in the peripancreatic fat. Immunohistochemistry showed nuclear/cytoplasmic positivity for beta-catenin, loss of E-cadherin, positivity for CD10 and CD56, and partial positivity for lymphoid enhancer-binding factor 1, supporting the diagnosis. The postoperative course was uneventful, and no evidence of recurrence was detected on short-term follow-up. This case suggests that giant solid pseudopapillary neoplasm may have been related to acute abdominal pain in the setting of intratumoral degeneration, hemorrhagic change, and local tension effect. Surgical strategy should balance oncologic safety, bleeding risk, and organ preservation. In patients requiring splenectomy, long-term infection prevention should include immunization planning, fever emergency counseling, and individualized antibiotic prophylaxis according to local guidance and risk stratification.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.