Evidence map›Paper›PMID 42528350›Full record

ArticleClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology2026

Occupational Stress in the Neuroticism-Burnout Link: An Exploratory Examination of Physiological Contributions.

Hyun Seo Lee, Taegyeong Lee, Koomin Kwon, Woo-Seok Ahn, Seung-Hwan Lee

Abstract read
In one paragraph

Article in Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hyun Seo LeeClinical Emotion and Cognition Research Laboratory, Inje University, Goyang, Korea.ORCID https://orcid.org/0000-0002-4321-2949
Taegyeong LeeClinical Emotion and Cognition Research Laboratory, Inje University, Goyang, Korea.ORCID https://orcid.org/0009-0006-2694-2583
Koomin KwonClinical Emotion and Cognition Research Laboratory, Inje University, Goyang, Korea.ORCID https://orcid.org/0009-0007-4323-1190
Woo-Seok AhnClinical Emotion and Cognition Research Laboratory, Inje University, Goyang, Korea.ORCID https://orcid.org/0009-0002-5855-2329
Seung-Hwan LeeClinical Emotion and Cognition Research Laboratory, Inje University, Goyang, Korea.ORCID https://orcid.org/0000-0003-0305-3709

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Burnout is a debilitating consequence of chronic occupational stress, yet few studies have simultaneously examined its psychological and physiological correlates. This study tested a mediation model linking neuroticism to burnout, with perceived stress as the primary mediator and wearable-derived physiological indices as an exploratory pathway. Methods: A total of 150 Korean working adults in high-stress occupations completed standardized measures of neuroticism, perceived occupational stress, and burnout. Resting-state frontal electroencephalography (EEG) and photoplethysmography (PPG) signals were collected using the Maumgyeol Basic wearable system to compute EEG indices and heart rate variability (HRV) features. Structural equation modeling, adjusting for age, evaluated parallel mediation via perceived stress and PPG-derived autonomic activity. Results: Neuroticism was associated with greater perceived stress and reduced PPG-based autonomic flexibility. Perceived stress significantly predicted burnout, whereas the PPG-burnout path showed a nonsignificant negative trend. The indirect effect of neuroticism through perceived stress was significant; in contrast, the indirect effect via PPG-derived autonomic activity did not reach statistical significance. Age was inversely associated with burnout. Conclusion: Findings identify perceived stress as the primary mediator linking neuroticism to occupational burnout. Although reduced autonomic flexibility was directionally consistent with burnout risk, the physiological pathway was not statistically supported and remains preliminary. Wearable biosignals may serve as complementary indicators of stress-related vulnerability.

Indexed as

Burnout, professionalElectroencephalographyHeart rate variabilityNeuroticismOccupational stressPhotoplethysmography

Identifiers

PMID42528350
PMCPMC13429769

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.