ArticleClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology2026
Predictors of Somatic Symptom Severity in Adult Psychiatric Outpatients: A Cross-sectional Heart Rate Variability and Quantitative Electroencephalography Study.
Article in Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To examine the relative contributions of clinical, autonomic, and neurophysiological variables to somatic symptom severity among adults with major depressive disorder (MDD) or attention-deficit/hyperactivity disorder (ADHD). Methods: We analyzed data from 103 outpatients (MDD = 55; ADHD = 48) who completed quantitative electroencephalography (QEEG), heart rate variability (HRV), and questionnaires (Patient Health Questionnaire-15, Beck Depression Inventory-II, Pittsburgh Sleep Quality Index, Korean Adult ADHD Rating Scale). Hierarchical regression models sequentially entered demographics, clinical symptoms, HRV total power, and QEEG beta-band coherence. Results: The final model explained 49.4% of the variance (adjusted R Conclusion: Sleep disturbance showed the strongest association with somatic symptoms, followed by female sex and depressive symptoms. Limited role of categorical diagnosis supports a dimensional framework. Reduced autonomic flexibility and disrupted cortical connectivity may underlie bodily distress, warranting confirmation through longitudinal studies.
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