Evidence map›Paper›PMID 42528292›Full record

ArticleTissue engineering. Part A2026

Exploring Spatial Patterning of Endothelial Cells and Trophoblast Cells in a Microfluidic Device.

Sia Mittal, Hannah S Theriault, Katie Karecki, Brendan A C Harley

Abstract read
In one paragraph

Article in Tissue engineering. Part A, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sia MittalDepartment Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.ORCID 0009-0002-9616-9179
Hannah S TheriaultDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Katie KareckiDepartment of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Brendan A C HarleyDepartment Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.ORCID 0000-0001-5458-154X

Funding

Physiomimetic Models of Endometrioma InitiationR01HD118600 · NICHD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Kathryn Bridges Harley Clancy, Brendan A. Harley · 2025 to 2026
$1.3M
Interdisciplinary Research Training at the Interface of Reproductive Sciences and BioengineeringT32HD108075 · NICHD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Indrani C Bagchi, Amy J Wagoner Johnson · 2024 to 2026
$794k
NICHD NIH HHS R01 HD118600NICHD NIH HHS T32 HD108075
6 · The paper itself

Abstract

Trophoblast invasion into the decidualized endometrium is an important aspect of blastocyst implantation necessary for a successful pregnancy. There are many processes involving the early implantation and invasion of trophoblast cells into the maternal decidua that are not well described. Here, we describe the development of a microfluidic model of the trophoblast-endometrial interface that can be used to quantify metrics of trophoblast cell invasion, endothelial cell motility, and the influence of decidualization hormones on these processes.

Indexed as

maternal–fetal interfacemicrofluidicspregnancytrophoblast invasion

Identifiers

PMID42528292
PMCPMC13474325

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.