Evidence map›Paper›PMID 42528206›Full record

ArticleThe Journal of reproduction and development2026

Somatic cell nuclear transfer as a complementary tool for genetic conservation of the Peruvian Paso horse.

Jenin V Cortez, Gleni T Segura Portocarrero, Nilton L Murga Valderrama, William Bardales, Ricardo Encina Ruiz, Carmen L Velásquez Castillo, Christopher G Grupen, Jorge L Maicelo Quintana

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of reproduction and development, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jenin V CortezLaboratory of Animal Biotechnology, Reproduction and Genetic Improvement, Livestock and Biotechnology Research Institute, Faculty of Zootechnical Engineering, Agribusiness and Biotechnology, National University Toribio Rodríguez de Mendoza, Amazonas, Peru.
Gleni T Segura PortocarreroLaboratory of Animal Biotechnology, Reproduction and Genetic Improvement, Livestock and Biotechnology Research Institute, Faculty of Zootechnical Engineering, Agribusiness and Biotechnology, National University Toribio Rodríguez de Mendoza, Amazonas, Peru.
Nilton L Murga ValderramaLaboratory of Animal Biotechnology, Reproduction and Genetic Improvement, Livestock and Biotechnology Research Institute, Faculty of Zootechnical Engineering, Agribusiness and Biotechnology, National University Toribio Rodríguez de Mendoza, Amazonas, Peru.
William BardalesLivestock and Biotechnology Research Institute, Faculty of Zootechnical Engineering, Agribusiness and Biotechnology, National University Toribio Rodríguez de Mendoza, Amazonas, Peru.
Ricardo Encina RuizLivestock and Biotechnology Research Institute, Faculty of Zootechnical Engineering, Agribusiness and Biotechnology, National University Toribio Rodríguez de Mendoza, Amazonas, Peru.
Carmen L Velásquez CastilloLivestock and Biotechnology Research Institute, Faculty of Zootechnical Engineering, Agribusiness and Biotechnology, National University Toribio Rodríguez de Mendoza, Amazonas, Peru.
Christopher G GrupenSydney School of Veterinary Science, Faculty of Science, The University of Sydney, NSW, Australia.
Jorge L Maicelo QuintanaLivestock and Biotechnology Research Institute, Faculty of Zootechnical Engineering, Agribusiness and Biotechnology, National University Toribio Rodríguez de Mendoza, Amazonas, Peru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Peruvian Paso horse, a breed of national significance in Peru known for its unique gait, has been selectively bred for nearly 500 years and now faces potential risks due to reduced genetic diversity. To investigate the potential of somatic cell nuclear transfer to enhance genetic conservation strategies, a program was initiated to produce cloned Peruvian Paso foals. Skin biopsies from a highly awarded stallion with exceptional breed-defining traits were used as the source of donor somatic cells. Of the 15 cloned embryos reconstructed, seven blastocysts were produced, and five were transferred to five recipient mares. Three pregnancies ensued, two of which resulted in the birth of healthy foals at 333 and 347 days of gestation. Cloned foals were genetically and phenotypically identical to the donor animal, demonstrating the successful application of this approach to support genetic conservation in a protected horse breed.

Indexed as

Cloning, OrganismNuclear Transfer TechniquesAnimalsBreedingConservation of Natural ResourcesEmbryo TransferFemaleHorsesPeruPregnancyConservation cloningEmbryo developmentEquineFoalPregnancy

Identifiers

PMID42528206
PMCPMC13677195

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.