Evidence map›Paper›PMID 42528108›Full record

ArticleBreastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine2026

Using the Information-Motivation-Behavioral Framework to Promote Rational Medicine Use Among Breastfeeding Women: A Quasi-Experimental Intervention Study in Uganda.

Ritah Nakijoba, Lynn M Atuyambe, Simon Peter Asiimwe, Paul Mubiru, Catherine Namubiru, Solome Nakazzi, Ronald Kiguba, Catriona Waitt

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Article in Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Ritah NakijobaInfectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda.ORCID 0000-0002-6626-0329
Lynn M AtuyambeDepartment of Community Health and Behavior Sciences, Makerere University School of Public Health, College of Health Sciences, Kampala, Uganda.
Simon Peter AsiimweInfectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda.
Paul MubiruInfectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda.
Catherine NamubiruInfectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda.
Solome NakazziInfectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda.
Ronald KigubaDepartment of Pharmacology and Therapeutics, Makerere University College of Health Sciences, Kampala, Uganda.
Catriona WaittInfectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda.

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundRational medicine use during breastfeeding remains a challenge, especially in low- and middle-income countries. Self-medication, incomplete dosing, inappropriate drug selection, poor adherence, and adverse drug reactions contribute to antimicrobial resistance. Although the Information-Motivation-Behavioral Skills (IMB) model has successfully influenced health behaviors, its application to promoting safe medicine practices among breastfeeding women in urban settings is limited. This study assessed the association of an IMB-based educational intervention with knowledge, attitudes, and practices related to medication use.

methodsA quasi-experimental study with intervention and control groups was conducted among 184 breastfeeding women (≥18 years) with infants ≤12 months attending six urban clinics in Kampala, Uganda. Participants were recruited using systematic random sampling and allocated to intervention and control groups. The intervention comprised 12 weekly IMB-based health education sessions delivered through lectures, group discussions, videos, and printed materials. The control group received standard health education. Outcomes were measured at baseline and at 3 months using structured Likert-scale questionnaires. Changes over time and between groups were analyzed using repeated-measures analysis of variance and mixed-effects regression models.

resultsBaseline characteristics were comparable between groups. At three months, greater improvements in knowledge were observed in the intervention group compared with the control group (89% versus 80%; Mean difference (MD) = 8.3; 95% confidence interval [CI]: 6.0-10.6), motivation (81% versus 70%; MD = 11.5; 95% CI: 8.6-14.4), and behavior (91% versus 81%; MD = 9.9; 95% CI: 7.3-12.5), all

conclusionThe IMB-based intervention improved women's knowledge, motivation, and practices, supporting the integration of such programs into routine health education.

Indexed as

Breastfeedingbreast milkinfantsinterventionlactationmedicationmodel

Identifiers

PMID42528108
PMCPMC7619408

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.