Evidence map›Paper›PMID 42527925›Full record

ArticleBMC surgery2026

Endovenous laser ablation versus ligation plus stripping or sclerotherapy for primary lower limb varicose veins: a multicentric three-arm propensity score matched analysis.

Walied Khereba, Almetwaly Ragab, Osama Moeen, Mohamed Ahmed Agena, Elsayed Hadhoud, Reda Othman Abbas, Ahmed Atef, Maisa A Abdel Wahab, Sameh E Elimam, Ahmed Khairy Sakr and 6 more

Abstract readMulticenter StudyComparative Study
In one paragraph

Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

16 authors.

Walied KherebaDepartment of Vascular Surgery, Faculty of Medicine, Al-Azhar University, New Damietta, Egypt.
Almetwaly RagabDepartment of Vascular Surgery, Faculty of Medicine, Al-Azhar University, New Damietta, Egypt.
Osama MoeenDepartment of Vascular Surgery, Faculty of Medicine, Al-Azhar University, New Damietta, Egypt.
Mohamed Ahmed AgenaDepartment of Vascular Surgery, Faculty of Medicine, Al-Azhar University, New Damietta, Egypt.
Elsayed HadhoudDepartment of Vascular Surgery, Faculty of Medicine, Al-Azhar University, New Damietta, Egypt.
Reda Othman AbbasDepartment of Vascular Surgery, Faculty of Medicine, Al-Azhar University, New Damietta, Egypt.
Ahmed AtefDepartment of Vascular Surgery, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
Maisa A Abdel WahabDepartment of Vascular Surgery, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.
Sameh E ElimamDepartment of Vascular Surgery, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.
Ahmed Khairy SakrDepartment of Vascular Surgery, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.
Shimaa M ElhalafawyDepartment of Vascular Surgery, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.
Ahmed Ibrahim BadranDepartment of Vascular Surgery, Faculty of Medicine, Tanta University, Tanta, Egypt.
Ahmed T M RadwanDepartment of Vascular Access & Renal Transplant Surgery, Birmingham University Hospital, Birmingham, UK.
Elsayed Mohamed Abd El-HamidDepartment of Radio-diagnosis, Faculty of Medicine, Al-Azhar University, New Damietta, Egypt.
Amr Bakr Mahmoud ElashryDepartment of Vascular Surgery, Faculty of Medicine for boys, Al Azhar University, Cairo, Egypt.
Mohamed Emad EldinDepartment of Vascular Surgery, Faculty of Medicine, Mansoura University, Mansoura, Egypt. memad100100@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimVaricose veins (VVs) are one of the most common consequences of chronic venous disease. The present multicentric three-arm study aimed to compare the clinical outcomes of endovenous laser ablation (EVLA) versus ligation plus stripping or sclerotherapy for primary lower limb VVs. PATIENT AND

methodsThe study included 300 patients with VVs. They received EVLA (GI, n = 100), ligation plus stripping (GII, n = 100) or ligation plus sclerotherapy (GIII, n = 100). Groups were matched using propensity score. The primary outcome measures were 1-year total occlusion and recurrence rates.

resultsAt 1 year follow up, no significant differences were found between the total occlusion rates for GI (75.0%), GII (76.0%) and GIII (83.0%). It was demonstrated that GII had significantly higher recurrence rate (24.0%) as compared to GI (6.0%) and GIII (5.0%). It was also found that GII group had significantly higher frequency of ecchymosis, hematoma and surgical site infection as compared to the other two groups. In contrast, GI had significantly higher frequency of skin ulceration/burn as compared to the other two groups. Also, it was found that GIII had significantly lower frequency of deep vein thrombosis than GI and GII.

conclusionLigation plus sclerotherapy achieved slightly better total occlusion rate in comparison to EVLA and ligation plus stripping while avoiding important side effects related to them mainly traumatic and thermal injury effects and recurrence.

Indexed as

Endovascular ProceduresLaser TherapyLower ExtremitySclerotherapyVaricose VeinsAdultAgedFemaleFollow-Up StudiesHumansLigationMaleMiddle AgedPropensity ScoreRecurrenceTreatment OutcomeLaser ablationSclerotherapyStrippingVaricose Veins. Ligation

Identifiers

PMID42527925
PMCPMC13420854

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