Evidence map›Paper›PMID 42527683›Full record

ArticleAesthetic plastic surgery2026

The Impact of Nicotine Usage Across Body Contouring Surgery Outcomes and Opioid Usage.

Angad S Sidhu, Avani A Chopra, Daniel J Konig, George S Corpuz, Cynthia Sung, Aanya Chopra, Cristiane M Ueno, Mary E Lester, Ivan Hadad

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Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Angad S Sidhu *Division of Plastic and Reconstructive Surgery, Indiana University School of Medicine, 545 Barnhill Drive, Emerson Hall 232, Indianapolis, IN, 46202, USA.ORCID http://orcid.org/0009-0007-9825-8964
Avani A Chopra *Penn State College of Medicine, Hershey, PA, USA.
Daniel J KonigDivision of Plastic and Reconstructive Surgery, Indiana University School of Medicine, 545 Barnhill Drive, Emerson Hall 232, Indianapolis, IN, 46202, USA.
George S CorpuzDivision of Plastic and Reconstructive Surgery, Indiana University School of Medicine, 545 Barnhill Drive, Emerson Hall 232, Indianapolis, IN, 46202, USA.
Cynthia SungDivision of Plastic and Reconstructive Surgery, Indiana University School of Medicine, 545 Barnhill Drive, Emerson Hall 232, Indianapolis, IN, 46202, USA.
Aanya ChopraPenn State College of Medicine, Hershey, PA, USA.
Cristiane M UenoDivision of Plastic and Reconstructive Surgery, Indiana University School of Medicine, 545 Barnhill Drive, Emerson Hall 232, Indianapolis, IN, 46202, USA.
Mary E LesterDivision of Plastic and Reconstructive Surgery, Indiana University School of Medicine, 545 Barnhill Drive, Emerson Hall 232, Indianapolis, IN, 46202, USA.
Ivan HadadDivision of Plastic and Reconstructive Surgery, Indiana University School of Medicine, 545 Barnhill Drive, Emerson Hall 232, Indianapolis, IN, 46202, USA. ihadad@iu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNicotine use is a well-established risk factor for surgical wound complications and overall postoperative morbidity;however, its impact on elective aesthetic procedures such as body contouring surgery remains poorly characterized.

methodsUsing a large de-identifi ed electronic health record database (TriNetX), adult patients who underwent bodycontouring procedures between 2005 and 2025 were identifi ed and propensity score matched based on history ofnicotine dependence. Postoperative outcomes at 90-days were compared between patients with and withoutnicotine dependence, including wound complications, complications requiring operative intervention, seroma,venous thromboembolism, and opioid prescriptions.

resultsA total of 110,287 patients were identifi ed. After matching, each cohort had 17,065 patients. At 90-dayspostoperatively, patients with nicotine dependence demonstrated signifi cantly higher odds of wound complications,wound complications requiring operative intervention, seroma formation, and opioid prescriptions compared to non-nicotine users. No signifi cant diff erences were observed in venous thromboembolism rates between groups.

conclusionThese fi ndings suggest that nicotine dependence is associated with increased postoperative morbidity followingbody contouring procedures, particularly with respect to wound-related complications and opioid utilization. Routinepreoperative nicotine screening, patient education, and cessation interventions may play an important role inmitigating postoperative complications and improving outcomes in patients undergoing elective aesthetic bodycontouring surgery Level of Evidence III This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Aesthetic surgeryBody contouringNicotineOpioidsPlastic surgeryTobacco

Identifiers

PMID42527683

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.