Evidence map›Paper›PMID 42527618›Full record

ArticleCardiovascular and interventional radiology2026

Evaluating the Predictive Value of Pre-procedural Diagnostic Nerve Blocks in Patients Undergoing Cryoneurolysis.

Shamar Young, Ahmet Gunkan, Sarah Placek, Lucas Struycken, Artyom Abramyan, Ilaria Vittoria De Martini, Jack Hannallah, Gregory Woodhead, Daniel Goldberg

Abstract read
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In one paragraph

Article in Cardiovascular and interventional radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shamar YoungDivision of Interventional Radiology, Department of Medical Imaging, University of Arizona Medical Center, 1501 N. Campbell Ave, P.O. Box 245067, Tucson, AZ, 85712, USA.
Ahmet GunkanDivision of Interventional Radiology, Department of Medical Imaging, University of Arizona Medical Center, 1501 N. Campbell Ave, P.O. Box 245067, Tucson, AZ, 85712, USA.ORCID http://orcid.org/0000-0002-6236-5633
Sarah PlacekDivision of Interventional Radiology, Department of Medical Imaging, University of Arizona Medical Center, 1501 N. Campbell Ave, P.O. Box 245067, Tucson, AZ, 85712, USA.
Lucas StruyckenDivision of Interventional Radiology, Department of Medical Imaging, University of Arizona Medical Center, 1501 N. Campbell Ave, P.O. Box 245067, Tucson, AZ, 85712, USA.
Artyom AbramyanDivision of Interventional Radiology, Department of Medical Imaging, University of Arizona Medical Center, 1501 N. Campbell Ave, P.O. Box 245067, Tucson, AZ, 85712, USA.
Ilaria Vittoria De MartiniDivision of Interventional Radiology, Department of Medical Imaging, University of Arizona Medical Center, 1501 N. Campbell Ave, P.O. Box 245067, Tucson, AZ, 85712, USA.
Jack HannallahDivision of Interventional Radiology, Department of Medical Imaging, University of Arizona Medical Center, 1501 N. Campbell Ave, P.O. Box 245067, Tucson, AZ, 85712, USA.
Gregory WoodheadDivision of Interventional Radiology, Department of Medical Imaging, University of Arizona Medical Center, 1501 N. Campbell Ave, P.O. Box 245067, Tucson, AZ, 85712, USA.
Daniel GoldbergDivision of Interventional Radiology, Department of Medical Imaging, University of Arizona Medical Center, 1501 N. Campbell Ave, P.O. Box 245067, Tucson, AZ, 85712, USA. dgoldberg@arizona.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the impact of pre-cryoneurolysis blocks by comparing outcomes between patients who underwent cryoneurolysis without a pretreatment block and those who underwent cryoneurolysis following a diagnostic block. MATERIALS AND

methodsA retrospective single-center analysis was performed of patients who underwent CT-guided cryoneurolysis for intractable abdominopelvic pain. Patients were categorized according to whether a pre-cryoneurolysis diagnostic block was performed. Clinical success was defined as an improvement in Visual Analog Scale (VAS) pain score of ≥ 3 points. Pre- and post-procedural pain scores and adverse events (AEs) were assessed.

resultsFor entire cohort, including 52 patients who received a pre-cryoneurolysis block and 43 patients who did not, mean VAS score improved from 8.4 ± 1.6 pre-procedurally to 3.9 ± 2.5 at 1 week (p < 0.001), 3.8 ± 2.7 at 1 month (p < 0.001), and 4.8 ± 3.2 at 3 months (p < 0.001) after cryoneurolysis. Use of a pre-cryoneurolysis-block was associated with a mean delay of 16.1 ± 13.5 days (range, 0-50) to cryoneurolysis. Clinical success rates did not differ significantly between the block and non-block groups at 1 week (76.6% [36/47] vs 78.4% [29/37], p = 1.0), 1 month (81.1% [30/37] vs 69.7% [23/33], p = 0.403), or 3 months (62.5% [15/24] vs 75.0% [15/20], p = 0.519). No AEs were observed.

conclusionCT-guided cryoneurolysis provides significant pain relief for cancer- and non-cancer-related chronic abdominopelvic pain, with comparable pain improvement regardless of whether a pre-cryoneurolysis diagnostic block is performed. When the pain source is clearly identified, direct cryoneurolysis may be a reasonable option.

Indexed as

Abdominal painCancer painCryoneurolysisPelvic painPudendal cryoneurolysisSplanchnic neurolysis

Identifiers

PMID42527618

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.