Evidence map›Paper›PMID 42527615›Full record

Observational studyCardiovascular and interventional radiology2026

Nonselective Intra-arterial CT Angiography Versus Selective Digital Subtraction Angiography for Detecting Neovascularization During Transarterial Embolization for Adhesive Capsulitis.

Wei-Chen Liao, Hao-Yu Huang, Yu-Hsin Chen, Han-Bin Huang, Wen-Jinn Liaw, Yi-Chih Hsu

Registry-linked trialAbstract readComparative StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Cardiovascular and interventional radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06509087 (The Combined Utility of Angio-CT and MRI in Managing Chronic Musculoskeletal Pain), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06509087 recruitingnot on this map

The Combined Utility of Angio-CT and MRI in Managing Chronic Musculoskeletal Pain: a Prospective Study to Evaluate the Efficacy of Transarterial Microembolization

TypeobservationalSponsorTri-Service General Hospital (TSGH)Ran2024 to 2027Enrolled60ConditionsChronic Musculoskeletal Disease, Transarterial Embolization, Magnetic Resonance Imaging, AngiographyArmsTransarterial microembolization (TAME)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Beyond Better Detection: A New Era for Musculoskeletal Embolization?Cardiovascular and interventional radiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wei-Chen LiaoDepartment of Radiology, Tri-Service General Hospital, National Defense Medical University, No. 325, Sec. 2, Cheng-Kung Rd, Neihu, Taipei, 114, Taiwan.
Hao-Yu HuangDepartment of Radiology, Tri-Service General Hospital, National Defense Medical University, No. 325, Sec. 2, Cheng-Kung Rd, Neihu, Taipei, 114, Taiwan.
Yu-Hsin ChenDepartment of Radiology, Tri-Service General Hospital, National Defense Medical University, No. 325, Sec. 2, Cheng-Kung Rd, Neihu, Taipei, 114, Taiwan.
Han-Bin HuangSchool of Public Health, College of Public Health, National Defense Medical University, Taipei, Taiwan.
Wen-Jinn LiawDepartment of Anesthesiology, Chung Shan Medical University Hospital, Taichung, Taiwan.
Yi-Chih HsuDepartment of Radiology, Tri-Service General Hospital, National Defense Medical University, No. 325, Sec. 2, Cheng-Kung Rd, Neihu, Taipei, 114, Taiwan. doc31578@gmail.com.ORCID http://orcid.org/0000-0003-1926-4818

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTransarterial embolization (TAE) for adhesive capsulitis requires precise detection of periarticular neovascularization, which is often inconspicuous on digital subtraction angiography (DSA). This study compared intra-arterial CT angiography (IA-CTA) with DSA for detecting synovial neovascularization during embolization. MATERIALS AND

methodsIn this prospective single-center study, 21 participants with adhesive capsulitis despite ≥ 3 months of conservative treatment were enrolled. Nonselective IA-CTA was performed from the mid-subclavian artery before selective DSA-guided embolization in a hybrid angio-CT suite. Six periarticular sites per shoulder were evaluated. Two radiologists independently assigned five-point scores for IA-CTA and DSA to establish the reference standard using a multimodality adjudication rule. Six radiology residents independently scored each modality. Diagnostic performance was compared using multireader multicase analysis; secondary endpoints were sensitivity, specificity, and reader agreement.

resultsTwenty-one participants (mean age, 61.6 ± 11.0 years; 15 women, 6 men) were included. Of 126 periarticular sites, 65 (51.6%) were positive by the reference standard. Reader-averaged area under the receiver operating characteristic curve (AUC) favored IA-CTA over DSA (0.901 vs. 0.769; p < 0.01). At the prespecified positivity threshold (score ≥ 4), reader-averaged sensitivity was 68.5% (95% CI: 57.0-79.7) with IA-CTA and 47.9% (95% CI: 36.9-57.7) with DSA (p = 0.01), whereas specificity was 95.4% (95% CI: 90.8-99.0) with IA-CTA and 92.3% (95% CI: 86.2-97.4) with DSA (p = 0.24). Inter-reader agreement favored IA-CTA over DSA (weighted κ 0.75 vs. 0.65; p < 0.01).

conclusionNonselective IA-CTA showed higher diagnostic performance, higher sensitivity, and better inter-reader agreement than selective DSA for detecting synovial neovascularization. LEVEL OF EVIDENCE: Level 4, diagnostic study. (ClinicalTrials.gov: NCT06509087).

Indexed as

Angiography, Digital SubtractionBursitisComputed Tomography AngiographyEmbolization, TherapeuticNeovascularization, PathologicAgedFemaleHumansMaleMiddle AgedProspective StudiesSensitivity and SpecificityAdhesive capsulitisComputed tomography angiographyDigital subtraction angiographyShoulderTransarterial embolization

Identifiers

PMID42527615

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.