Evidence map›Paper›PMID 42527607›Full record

ArticleNature2026

Diverse bacterial pattern recognition receptors sense the core phage proteome.

Hyunbin Lee, Sofia Luengo-Woods, Jianxiu Zhang, Kira S Makarova, Yuri I Wolf, Collin Chiu, Simone A Evans, Junyi Chen, Haopeng Xiao, Liang Feng and 2 more

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. How bacterial immune systems sense phage infection.Nature reviews. Microbiology · 2026
    Review
  2. Article
  3. Balancing of immune activation and suppression during phage infection.bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Hyunbin Lee *Department of Biochemistry, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0009-0006-1911-435X
Sofia Luengo-Woods *Department of Biochemistry, Stanford University, Stanford, CA, USA.
Jianxiu Zhang *Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-1864-7510
Kira S MakarovaComputational Biology Branch, Division of Intramural Research, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-8174-2844
Yuri I WolfComputational Biology Branch, Division of Intramural Research, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-0247-8708
Collin ChiuDepartment of Biochemistry, Stanford University, Stanford, CA, USA.
Simone A EvansDepartment of Biochemistry, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-4975-8747
Junyi ChenDepartment of Biochemistry, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0001-7453-6623
Haopeng XiaoDepartment of Biochemistry, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-4166-647X
Liang FengDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0001-6171-2050
Eugene V KooninComputational Biology Branch, Division of Intramural Research, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-3943-8299
Alex GaoDepartment of Biochemistry, Stanford University, Stanford, CA, USA. algao@stanford.edu.ORCID http://orcid.org/0000-0002-3579-0327

Funding

Defining the landscape and mechanisms of redox regulation of metabolism during agingR00AG073461 · NIA · STANFORD UNIVERSITY · PI Haopeng Xiao · 2025 to 2026
$497k
NIA NIH HHS R00 AG073461
6 · The paper itself

Abstract

Recognition of foreign molecules inside cells is critical for immunity across all domains of life. Proteins of the STAND NTPase superfamily

Indexed as

BacteriophagesProteomeReceptors, Pattern RecognitionSalmonella entericaViral ProteinsCapsid ProteinsCryoelectron MicroscopyModels, MolecularPeptide Elongation Factor TuPhylogenyCapsid ProteinsPeptide Elongation Factor TuProteomeReceptors, Pattern RecognitionViral Proteins

Identifiers

PMID42527607
PMCPMC13581612

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.