Evidence map›Paper›PMID 42527597›Full record

ArticleNature2026

Sequential reading of a stepwise-shortened peptide immobilized on nanopore.

Jialu Chen, Hanhan Zhang, Kefan Wang, Tian Li, Wen Sun, Zixuan Wang, Xinmeng Gao, Zhenyuan Cao, Yusheng Ouyang, Lang Yao and 9 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Jialu Chen *State Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.ORCID http://orcid.org/0000-0001-9847-5802
Hanhan Zhang *State Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.
Kefan Wang *State Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.
Tian LiState Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.
Wen SunState Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.
Zixuan WangState Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.
Xinmeng GaoState Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.
Zhenyuan CaoState Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.
Yusheng OuyangState Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.
Lang YaoState Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.
Yifan WangState Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.
Yunqi XiaoState Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.ORCID http://orcid.org/0000-0003-1473-9036
Ruidong LiState Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.
Xingwang AnState Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.ORCID http://orcid.org/0009-0007-8719-3181
Xinyi DaiState Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.
Lulu ZhaoState Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.
Lu QianState Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.
Panke ZhangState Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.ORCID http://orcid.org/0000-0001-8562-9972
Shuo HuangState Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry, Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China. shuo.huang@nju.edu.cn.ORCID http://orcid.org/0000-0001-6133-7027

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate decoding of peptide sequences is crucial in proteomics. However, achieving this goal is a technical challenge, owing to the compositional and structural complexity of peptides

Indexed as

Immobilized ProteinsNanoporesPeptidesAmino Acid SequenceMutationMycobacterium smegmatisNickelNitrilotriacetic AcidPorinsProteomicsImmobilized ProteinsmspA protein, Mycobacterium smegmatisNickelNitrilotriacetic AcidPeptidesPorins

Identifiers

PMID42527597

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.