Evidence map›Paper›PMID 42527546›Full record

ReviewJournal of perinatology : official journal of the California Perinatal Association2026

Silent struggles of internalizing disorders in survivors of neonatal hypoxic ischemic encephalopathy: a scoping review.

Nursena Yabalar, Irem Isik, Nur Aycan, Mary Hitchcock, Sarah Elizabeth Nigro, Alanna M Kessler-Jones, Pelin Cengiz, Jonathan J Mietchen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nursena Yabalar *Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Irem Isik *Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.ORCID http://orcid.org/0009-0008-6652-3927
Nur AycanDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.ORCID http://orcid.org/0000-0001-7947-9496
Mary HitchcockEbling Library for the Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.ORCID http://orcid.org/0000-0002-8254-388X
Sarah Elizabeth NigroDepartment of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Alanna M Kessler-JonesDepartment of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.ORCID http://orcid.org/0000-0003-0116-8422
Pelin Cengiz *Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA. cengiz@pediatrics.wisc.edu.
Jonathan J Mietchen *Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.ORCID http://orcid.org/0000-0002-1410-7883

Funding

Sex Differences in Neurotrophin Mediated Neonatal Neuroprotection: Role of ER AlphaR01NS111021 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI CENGIZ, PELIN · 2019 to 2023
$1.7M
NINDS NIH HHS R01 NS111021
6 · The paper itself

Abstract

Internalizing disorders in children and adolescents include anxiety, depression, and somatic symptoms. Early identification is essential to prevent long-term mental health challenges. Hypoxic-ischemic encephalopathy (HIE) has been associated with an increased risk of internalizing disorders in early life. This scoping review summarized the literature on internalizing disorders in HIE survivors, highlighting the assessment methods and psychological outcomes. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for scoping reviews and included peer-reviewed studies reporting internalizing symptoms in HIE survivors. Five major databases were searched, and study quality was assessed using the Newcastle-Ottawa Scale. Of the 2917 studies screened, twelve met the inclusion criteria. Our review revealed variability in internalizing symptoms, but nine of the 12 studies showed that HIE survivors had higher internalizing symptoms. This review revealed substantial variability across studies, underscoring the need for more standardized assessment tools and early screening during early childhood.

Identifiers

PMID42527546

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.