Evidence map›Paper›PMID 42527505›Full record

Articlenpj health systems2026

Feasibility assessment of an EHR-integrated research platform for prospective data collection in community oncology practice.

Majd T Ghanim, Daniel Sanchez, Claire Dykas, Fredrik Borgsten, Abhishek Dabral, Mariana Fernandez, Laura Hester, Maneet Kaur, Lakshmikanth Katragadda, Yichen Lu and 7 more

Abstract read
In one paragraph

Article in npj health systems, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Majd T GhanimFlatiron Health, New York, NY, USA.
Daniel SanchezJohnson & Johnson, New Brunswick, NJ, USA.
Claire DykasFlatiron Health, New York, NY, USA.
Fredrik BorgstenJohnson & Johnson, Raritan, NJ, USA.
Abhishek DabralFlatiron Health, New York, NY, USA.
Mariana FernandezJohnson & Johnson, Madrid, Spain.
Laura HesterJohnson & Johnson, New Brunswick, NJ, USA.
Maneet KaurFlatiron Health, New York, NY, USA.
Lakshmikanth KatragaddaClearview Cancer Institute, Huntsville, AL, USA.
Yichen LuFlatiron Health, New York, NY, USA.
Amanda Rodriguez-SullivanFlatiron Health, New York, NY, USA.
Melanie RothschildJohnson & Johnson, New Brunswick, NJ, USA.
Paul M SalcuniFlatiron Health, New York, NY, USA.
Natalie SalituroFlatiron Health, New York, NY, USA.
Richard M ZunigaNew York Cancer and Blood Specialists, Babylon, NY, USA.
Neal J MeropolFlatiron Health, New York, NY, USA. nmeropol@flatiron.com.
Ashita S BataviaJohnson & Johnson, New Brunswick, NJ, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-approval observational studies that rely on traditional data collection approaches may be burdensome for community oncology settings with limited research infrastructure. We conducted a prospective observational study using an EHR-integrated platform to evaluate its feasibility for streamlining data collection in community oncology. We were able to capture high-quality data on infusion-related reactions in patients with multiple myeloma receiving daratumumab. The EHR-integrated platform included centralized patient identification, automated EHR-to-electronic data capture system data transfer, and centralized abstraction services. Over 11 months, 82 patients enrolled at four US community oncology sites, with 30.5% identifying as Black or Hispanic. Across 4568 essential data points: missingness accounted for 0.59%, 91% of data points were eligible for automated transfer, median transfer time for structured data was 1.7 days, and query frequency was <2% with a median resolution time of 5.1 days. This pilot study demonstrated that EHR-integrated platforms can be operationalized in community oncology settings with high data completeness and rapid, diverse enrollment, expanding access to clinical trials outside traditional research centers and producing more generalizable results.

Identifiers

PMID42527505
PMCPMC13354148

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.