Evidence map›Paper›PMID 42527499›Full record

Reviewnpj health systems2026

Facilitators of, barriers to and strategies for health-system guidance implementation: a critical interpretive synthesis.

Qi Wang, Junjie Ren, Xinyu Huang, Kehu Yang, Yaolong Chen, Michael G Wilson, Holger J Schünemann, John N Lavis

Abstract readReview
In one paragraph

Review in npj health systems, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qi WangMcMaster Health Forum, McMaster University, Hamilton, ON, Canada. qiwang92@hku.hk.
Junjie RenDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Xinyu HuangCentre for Evidence-Based Social Science/Center for Health Technology Assessment, School of Public Health, Lanzhou University, Lanzhou, China.
Kehu YangCentre for Evidence-Based Social Science/Center for Health Technology Assessment, School of Public Health, Lanzhou University, Lanzhou, China.
Yaolong ChenResearch Unit of Evidence-Based Evaluation and Guidelines, Chinese Academy of Medical Sciences (2021RU017), School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Michael G WilsonMcMaster Health Forum, McMaster University, Hamilton, ON, Canada.
Holger J SchünemannDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
John N LavisMcMaster Health Forum, McMaster University, Hamilton, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to develop a theoretical framework to support the implementation of health-system guidance, contributing to broader efforts to promote evidence-informed policymaking in health systems. A critical interpretive synthesis was conducted to identify relevant literature from 11 databases and gray literature sources. The documents were assessed for relevance and quality, and data were extracted and synthesized using an interpretive analytic method. Based on the synthesized data, the framework was developed and subsequently refined by the authors. A total of 21 documents published from 2004 to 2024 were included, with 15 (71%) empirical studies and six (29%) non-empirical. The resulting theoretical framework for supporting health-system guidance implementation identified 10 facilitators, 10 barriers, nine combined facilitators and barriers, and 11 strategies across six levels: political system, health system, community, organizational, providers and patients/public. This framework offers a structured approach to comprehensively understanding the various factors and levels involved in health-system guidance implementation. With further development into a practical tool, it may help inform implementation efforts across diverse topics and contexts.

Identifiers

PMID42527499
PMCPMC13354161

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.