Evidence map›Paper›PMID 42527442›Full record

Reviewnpj health systems2025

Trust in AI-assisted health systems and AI's trust in humans.

Madeline Sagona, Tinglong Dai, Mario Macis, Michael Darden

Abstract readReview
In one paragraph

Review in npj health systems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. A pragmatic risk-stratified framework for using large language models in intensive care medicine: A narrative review.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Madeline SagonaBloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Tinglong DaiHopkins Business of Health Initiative, Johns Hopkins University, Washington, DC, USA. dai@jhu.edu.ORCID http://orcid.org/0000-0001-9248-5153
Mario MacisHopkins Business of Health Initiative, Johns Hopkins University, Washington, DC, USA.
Michael DardenHopkins Business of Health Initiative, Johns Hopkins University, Washington, DC, USA.

Funding

Office of Vice Provost for Research, Johns Hopkins University Discovery Award
6 · The paper itself

Abstract

Artificial intelligence (AI) is reshaping healthcare, promising improved diagnostics, personalized treatments, and streamlined operations. Yet a lack of trust remains a persistent barrier to widespread adoption. This Perspective examines the web of trust in AI-assisted healthcare systems, exploring the relationships it shapes, the systemic inequalities it can reinforce, and the technical challenges it poses. We highlight the bidirectional nature of trust, in which both patients and providers must trust AI systems, while these systems rely on the quality of human input to function effectively. Using models of care-seeking behavior, we explore the potential of AI to affect patients' decisions to seek care, influence trust in healthcare providers and institutions, and affect diverse demographic and clinical settings. We argue that addressing trust-related challenges requires rigorous empirical research, equitable algorithm design, and shared accountability frameworks. Ultimately, AI's impact hinges not just on technical progress but on sustaining trust, which may erode if biases persist, transparency falters, or incentives misalign.

Identifiers

PMID42527442
PMCPMC13354213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.